Cut Your Losses: Spastin Mediates Branch-Specific Axon Loss

Meltzer Hagar; Schuldiner Oren

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Cut Your Losses: Spastin Mediates Branch-Specific Axon Loss

机译：减少损失：Spastin调解特定于分支机构的轴突损失

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In this issue of Neuron, Brill et al. (2016) demonstrate that, during synapse elimination in the developing neuromuscular junction, branch-specific microtubule destabilization results in arrested axonal transport and induces axon branch loss. This process is mediated in part by the neurodegeneration-associated, micro-tubule-severing protein spastin.

机译：在本期《神经元》中，Brill等人。（2016）证明，在发展中的神经肌肉接头的突触消除过程中，分支特异性微管失稳导致轴突运输被阻滞并引起轴突分支丢失。该过程部分地由与神经退行相关的，微管切断蛋白spastin介导。

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《Neuron》 |2016年第4期|共5页
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Meltzer Hagar; Schuldiner Oren;
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正文语种 eng
中图分类神经病学;
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1. Cut Your Losses: Spastin Mediates Branch-Specific Axon Loss [J] . Meltzer Hagar, Schuldiner Oren Neuron . 2016,第4期

机译：减少损失：Spastin调解特定于分支机构的轴突损失
2. BMP- and neuropilin 1-mediated motor axon navigation relies on spastin alternative translation [J] . Jardin Nicolas, Giudicelli Francois, Ten Martin Daniel, Development . 2018,第17期

机译：BMP-和Neuropilin 1介导的电动机轴突导航依靠Spastin替代翻译
3. The IL-1 pathway is a key mediator of axon degeneration and vision loss in a mouse model of indirect traumatic optic neuropathy. [J] . Rex Tonia S., Bernardo-Colon Alexandra, Vest Victoria, Investigative ophthalmology & visual science . 2018,第9期

机译：IL-1途径是间接创伤性视神经病变的小鼠模型中的轴突变性和视觉损失的关键介体。
4. High-temperature acoustic loss in. AT-cut, BT-cut and SC-cut quartz resonators [C] . Martin, J.J., Lopez, Frequency Control Symposium and PDA Exhibition, 2001. Proceedings of the 2001 IEEE International . 2001

机译：AT切，BT切和SC切石英谐振器中的高温声损耗
5. To Cut or Not to Cut: The Association Between Weight Loss and Cardiometabolic Health in Adolescents and Adults After Roux-En-Y Gastric Bypass [D] . Brissman, Markus. 2021

机译：切割或不切割：在Roux-Zh-Y胃旁路后青少年和成人体重减轻和心肌截止的关联
6. Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination [O] . Monika S. Brill, Tatjana Kleele, Laura Ruschkies, -1

机译：分支特定的微管去稳定介导神经肌肉突触消除过程中的轴突分支损失。
7. Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination [O] . Brill, Monika S., Kleele, Tatjana, Ruschkies, Laura, 2016

机译：分支特定的微管去稳定介导神经肌肉突触消除过程中的轴突分支损失。

Cut Your Losses: Spastin Mediates Branch-Specific Axon Loss

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