Gating of GIRK channels: details of an intricate, membrane-delimited signaling complex.

Sadja R; Alagem N; Reuveny E

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Gating of GIRK channels: details of an intricate, membrane-delimited signaling complex.

机译：GIRK通道的门控：复杂的，以膜分隔的信号转导复合体的详细信息。

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G protein-coupled inwardly rectifying potassium channels (GIRK/Kir3) are important elements in controlling cellular excitability. In recent years, tremendous progress has been made toward understanding various components involved in channel activation, modulation, and signaling specificity. In this review, we summarize these recent findings and attempt to put them in context with recently available structural data.

机译：G蛋白偶联的内向整流钾通道（GIRK / Kir3）是控制细胞兴奋性的重要元素。近年来，在理解与通道激活，调制和信令特异性有关的各种组件方面已经取得了巨大的进步。在这篇综述中，我们总结了这些最近的发现，并试图将它们与最近可用的结构数据相结合。

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《Neuron》 |2003年第1期|共4页
作者
Sadja R; Alagem N; Reuveny E;
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正文语种 eng
中图分类基础医学;
关键词
GTP-Binding Proteins; Ion Channel Gating; Potassium Channels; Signal Transduction; GTP-结合蛋白质类; 离子通道闸门; 钾通道; 信号传递;

机译：GTP-Binding Proteins;Ion Channel Gating;Potassium Channels;Signal Transduction;GTP-结合蛋白质类;离子通道闸门;钾通道;信号传递;

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1. Gating of GIRK channels: details of an intricate, membrane-delimited signaling complex. [J] . Sadja R, Alagem N, Reuveny E Neuron . 2003,第1期

机译：GIRK通道的门控：复杂的，以膜分隔的信号转导复合体的详细信息。
2. Functional and Biochemical Evidence for G-protein-gated Inwardly Rectifying K+ (GIRK) Channels Composed of GIRK2 and GIRK3* [J] . Tanya M. Jelacic, Matthew E. Kennedy, Kevin Wickman, The Journal of biological chemistry . 2000,第46期

机译：GIRK2和GIRK3组成的G蛋白门控的内向整流K +（GIRK）通道的功能和生化证据*
3. G-protein-gated potassium (GIRK) channels containing the GIRK2 subunit are control hubs for pharmacologically induced hypothermic responses. [J] . Costa AC, Stasko MR, Stoffel M, The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2005,第34期

机译：包含GIRK2亚基的G蛋白门控钾（GIRK）通道是药理学诱导的低温反应的控制中心。
4. The modulation of GIRK channels by halothane is essentially determined by its C terminus [C] . Lukas G. Weigl, Sergej Milovic, Bibiane Steinecker-Frohnwieser, International Conference on Basic and Systemic Mechanisms of Anesthesia . 2005

机译：氟烷的GIRK频道的调制基本上由其C Terminus确定
5. Development of Molecular Tools for the Investigation of G protein-gated Inwardly Rectifying Potassium (GIRK) Channels. [D] . Ramos-Hunter, Susan Joanne. 2017

机译：用于研究G蛋白门控的内向整流钾（GIRK）通道的分子工具的开发。
6. Agonist-induced Localization of Gq-coupled Receptors and G Protein-gated Inwardly Rectifying K+ (GIRK) Channels to Caveolae Determines Receptor Specificity of Phosphatidylinositol 45-Bisphosphate Signaling [O] . Shanyu Cui, Won-Kyung Ho, Seong-Tae Kim, 2010

机译：激动剂诱导的Gq耦合受体和G蛋白门控的内向整流K +（GIRK）通道向小窝的定位确定了磷脂酰肌醇45-双磷酸信号的受体特异性。
7. Gating of GIRK Channels Details of an Intricate, Membrane-Delimited Signaling Complex [O] . Sadja Rona, Alagem Noga, Reuveny Eitan 2003

机译：GIRK通道的门控复杂的，以膜分隔的信令复合体的详细信息
8. Viscous Hydrodynamic Model of Non-linear Plasma Oscillations in Two- Dimensional Gated Conduction Channels and Application to the Detection of Terahertz Signals [R] . Rudin, S. 2010

机译：二维门控导通道中非线性等离子体振荡的粘性流体动力学模型及其在太赫兹信号检测中的应用

Gating of GIRK channels: details of an intricate, membrane-delimited signaling complex.

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