Associative fear learning enhances sparse network coding in primary sensory cortex

GdalyahuA.; TringE.; PolackP.-O.; GruverR.; GolshaniP.; FanselowM.S.; SilvaA.J.; TrachtenbergJ.T.

首页> 外文期刊>Neuron >Associative fear learning enhances sparse network coding in primary sensory cortex

【24h】

Associative fear learning enhances sparse network coding in primary sensory cortex

机译：联想恐惧学习增强了初级感觉皮层的稀疏网络编码

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Several models of associative learning predict that stimulus processing changes during association formation. How associative learning reconfigures neural circuits in primary sensory cortex to " learn" associative attributes of a stimulus remains unknown. Using 2-photon in vivo calcium imaging to measure responses of networks of neurons in primary somatosensory cortex, we discovered that associative fear learning, in which whisker stimulation is paired with foot shock, enhances sparse population coding and robustness of the conditional stimulus, yet decreases total network activity. Fewer cortical neurons responded to stimulation of the trained whisker than in controls, yet their response strength was enhanced. These responses were not observed in mice exposed to a nonassociative learning procedure. Our results define how the cortical representation of a sensory stimulus is shaped by associative fear learning.

机译：联想学习的几种模型预测，刺激过程在联想形成过程中会发生变化。关联学习如何重新配置初级感觉皮层中的神经回路以“学习”刺激的关联属性仍然未知。使用2光子体内钙成像来测量原代体感皮层中神经元网络的反应，我们发现将晶须刺激与足部震颤结合在一起的联想恐惧学习增强了稀疏的种群编码和条件刺激的鲁棒性，但仍降低了总网络活动。较少的皮质神经元对经训练的晶须的刺激做出的反应比对照组少，但它们的反应强度得到了增强。在暴露于非联想学习程序的小鼠中未观察到这些反应。我们的结果定义了联想刺激学习如何塑造感觉刺激的皮质表征。

著录项

来源
《Neuron》 |2012年第1期|共12页
作者
GdalyahuA.; TringE.; PolackP.-O.; GruverR.; GolshaniP.; FanselowM.S.; SilvaA.J.; TrachtenbergJ.T.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类神经病学;
关键词

相似文献

外文文献
中文文献
专利

1. Associative fear learning enhances sparse network coding in primary sensory cortex [J] . GdalyahuA., TringE., PolackP.-O., Neuron . 2012,第1期

机译：联想恐惧学习增强了初级感觉皮层的稀疏网络编码
2. Learning Enhances Sensory and Multiple Non-sensory Representations in Primary Visual Cortex [J] . Poort Jasper, Khan Adil G., Pachitariu Marius, Neuron . 2015,第6期

机译：学习增强了主要视觉皮层中的感官和多个非感官表示
3. Associative learning shapes the neural code for stimulus magnitude in primary auditory cortex. [J] . Polley DB, Heiser MA, Blake DT, Proceedings of the National Academy of Sciences of the United States of America . 2004,第46期

机译：联想学习塑造了初级听觉皮层刺激大小的神经代码。
4. Barndorff-Nielsen diffusions model neurons in primary sensory cortex [C] . Toby Berger, Mustafa Sungkar Information Theory and Applications Workshop . 2016

机译：Barndorff-Nielsen扩散模拟初级感觉皮层中的神经元
5. Specific associative representational plasticity in the primary auditory cortex: The role of learning strategy and a function of cortical area gain for memory. [D] . Bieszczad, Katarzyna Maria. 2010

机译：在主要听觉皮层的特定联想代表性可塑性：学习策略的作用和记忆的皮质面积增加的功能。
6. Associative fear learning enhances sparse network coding in primary sensory cortex [O] . Amos Gdalyahu, Elaine Tring, Pierre-Olivier Polack, -1

机译：联想恐惧学习提高稀疏网络初级感觉皮层编码
7. Associative Fear Learning Enhances Sparse Network Coding in Primary Sensory Cortex [O] . Gdalyahu Amos, Tring Elaine, Polack Pierre-Olivier, 2012

机译：联想恐惧学习增强了初级感觉皮层的稀疏网络编码。
8. Sensory Systems Neuroscientists Face One Fundamental Puzzle on Their Desks: How Primary Sensory Cortex Balances the Weights on Extrinsic and Intrinsic Sources of Information. [R] . Lee, S., Blake, R. 2013

机译：感觉系统神经科学家在他们的办公桌上面对一个基本难题：初级感觉皮层如何平衡外在和内在信息来源的权重。

Associative fear learning enhances sparse network coding in primary sensory cortex

摘要

著录项

相似文献

相关主题

期刊订阅