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首页> 外文期刊>Neuron >Radial glial cells defined and major intermediates between embryonic stem cells and CNS neurons.
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Radial glial cells defined and major intermediates between embryonic stem cells and CNS neurons.

机译:defined神经胶质细胞是胚胎干细胞和中枢神经系统神经元之间的主要中间体。

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摘要

Radial glial cells have been identified as a major source of neurons during development. Here, we review the evidence for the distinct "glial" nature of radial glial cells and contrast these cells with their progenitors, the neuroepithelial cells. Recent results also suggest that not only during neurogenesis in vivo, but also during the differentiation of cultured embryonic stem cells toward neurons, progenitors with clear glial antigenic characteristics act as cellular intermediates.
机译:development神经胶质细胞已被确定为发育过程中神经元的主要来源。在这里,我们回顾了放射状神经胶质细胞独特的“神经胶质”性质的证据,并将这些细胞与其祖细胞,神经上皮细胞进行了对比。最近的研究结果还表明,不仅在体内神经发生过程中,而且在培养的胚胎干细胞向神经元的分化过程中,具有明显神经胶质抗原特性的祖细胞都充当细胞中间体。

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