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首页> 外文期刊>Neuron >The psychiatric GWAS consortium: big science comes to psychiatry.
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The psychiatric GWAS consortium: big science comes to psychiatry.

机译:精神科GWAS财团:精神病学进入了大科学领域。

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摘要

The Psychiatric GWAS Consortium was founded with the aim of conducting statistically rigorous and comprehensive GWAS meta-analyses for five major psychiatric disorders: ADHD, autism, bipolar disorder, major depressive disorder, and schizophrenia. In the era of GWAS and high-throughput genomics, a major trend has been the emergence of collaborative, consortia approaches. Taking advantage of the scale that collaborative consortia approaches can bring to a problem, the PGC has been a major driver in psychiatric genetics and provides a model for how similar approaches may be applied to other disease communities.
机译:精神科GWAS联盟的成立是为了对五种主要的精神科疾病进行统计上严格而全面的GWAS荟萃分析:多动症,自闭症,躁郁症,重度抑郁症和精神分裂症。在GWAS和高通量基因组学时代,协作的联盟方法的出现是一个主要趋势。利用协作财团方法可能会带来问题的规模,PGC一直是精神病学遗传学的主要推动力,并为将类似方法应用于其他疾病社区提供了模型。

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