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Nonlinear denoising and analysis of neuroimages with kernel principal component analysis and pre-image estimation

机译:神经核的非线性降噪与核主成分分析和图像前估计

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We investigate the use of kernel principal component analysis (PCA) and the inverse problem known as pre-image estimation in neuroimaging: i) We explore kernel PCA and pre-image estimation as a means for image denoising as part of the image preprocessing pipeline. Evaluation of the denoising procedure is performed within a data-driven split-half evaluation framework. ii) We introduce manifold navigation for exploration of a nonlinear data manifold, and illustrate how pre-image estimation can be used to generate brain maps in the continuum between experimentally defined brain states/classes. We base these illustrations on two fMRI BOLD data sets - one from a simple finger tapping experiment and the other from an experiment on object recognition in the ventral temporal lobe.
机译:我们研究了核主成分分析(PCA)的使用以及在神经影像学中被称为图像前估计的反问题:i)我们探索了内核PCA和图像前估计作为图像预处理管道一部分的图像去噪方法。去噪过程的评估是在数据驱动的半分评估框架内进行的。 ii)我们介绍了用于导航非线性数据流形的流形导航,并说明了如何使用图像前估计在实验定义的脑状态/类之间的连续体中生成脑图。我们将这些插图基于两个fMRI BOLD数据集-一个来自简单的手指敲击实验,另一个来自有关腹颞叶物体识别的实验。

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