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首页> 外文期刊>NeuroImage >Accelerated cerebral white matter development in preterm infants: a voxel-based morphometry study with diffusion tensor MR imaging.
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Accelerated cerebral white matter development in preterm infants: a voxel-based morphometry study with diffusion tensor MR imaging.

机译：早产儿脑白质的加速发展：基于体素的形态学研究，具有弥散张量MR成像。

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摘要

Twenty-seven preterm infants were compared to 10 full-term infants at term equivalent age using a voxel-based analysis of diffusion tensor imaging of the brain. Preterm infants exhibited higher fractional anisotropy values, which may suggest accelerated maturation, in the location of the sagittal stratum. While some earlier findings in preterm infants have suggested developmental delays, the results of this study are more consistent with accelerated white matter development, possibly as a result of increased sensorimotor stimulation in the extrauterine environment. These results are the first to suggest that the increased intensity of stimulation associated with preterm birth may advance the process of white matter maturation in the human brain. Questions remain about whether these findings reflect acceleration of the process of white matter maturation generally, or localized alterations induced specifically by activity in affected pathways.
机译：使用基于体素的大脑弥散张量成像分析，将二十七名早产儿与十名足月同等年龄的足月儿进行了比较。早产儿在矢状位处表现出较高的分数各向异性值，这可能表明成熟加快。尽管早产儿的一些早期发现提示发育迟缓，但这项研究的结果与白质加速发展更为一致，这可能是由于宫外环境中感觉运动刺激增加所致。这些结果首次表明早产引起的刺激强度增加可能会促进人脑白质成熟过程。这些发现是否反映出一般情况下白质成熟过程的加速，还是由受影响途径中的活性特异性诱导的局部改变尚存疑问。

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