• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>New biotechnology >Sophorolipid biosurfactants: Possible uses as antibacterial and antibiofilm agent
【24h】

Sophorolipid biosurfactants: Possible uses as antibacterial and antibiofilm agent

机译：槐糖脂生物表面活性剂：可能用作抗菌和抗生物膜剂

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Biosurfactants are amphipathic, surface-active molecules of microbial origin which accumulate at interfaces reducing interfacial tension and leading to the formation of aggregated micellular structures in solution. Some biosurfactants have been reported to have antimicrobial properties, the ability to prevent adhesion and to disrupt biofilm formation. We investigated antimicrobial properties and biofilm disruption using sophorolipids at different concentrations. Growth of Gram negative Cupriavidus necator ATCC 17699 and Gram positive Bacillus subtilis BBK006 were inhibited by sophorolipids at concentrations of 5% v/v with a bactericidal effect. Sophorolipids ( 5% v/v) were also able to disrupt biofilms formed by single and mixed cultures of B. subtilis BBK006 and Staphylococcus aureus ATCC 9144 under static and flow conditions, as was observed by scanning electron microscopy. The results indicated that sophorolipids may be promising compounds for use in biomedical application as adjuvants to other antimicrobial against some pathogens through inhibition of growth and/or biofilm disruption.
机译：生物表面活性剂是微生物来源的两亲性表面活性分子，它们在界面处聚集，从而降低界面张力并导致溶液中聚集的微细胞结构形成。据报道，某些生物表面活性剂具有抗菌性能，具有防止粘附和破坏生物膜形成的能力。我们调查了使用不同浓度的槐糖脂的抗菌性能和生物膜破坏。浓度为5％v / v的槐糖脂可抑制革兰氏阴性Cupriavidus necator ATCC 17699和枯草芽孢杆菌BBK006的生长，并具有杀菌作用。如通过扫描电子显微镜观察到的那样，槐糖脂（5％v / v）还能够破坏由枯草芽孢杆菌BBK006和金黄色葡萄球菌ATCC 9144的单一和混合培养物形成的生物膜。结果表明，槐糖脂可能是有希望的化合物，可通过抑制生长和/或生物膜破坏，作为抗某些病原体的其他抗菌剂的佐剂。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号