Octodon degus. A useful animal model for social-affective neuroscience research: basic description of separation distress, social attachments and play.

Colonnello V; Iacobucci P; Fuchs T; Newberry RC; Panksepp J

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Octodon degus. A useful animal model for social-affective neuroscience research: basic description of separation distress, social attachments and play.

机译：Octodon degus。用于社交情感神经科学研究的有用动物模型：分离困扰，社交依恋和游戏的基本描述。

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A challenge for social-affective neuroscience programs is to identify simple and yet valid animal models for studying the expression of basic social emotions and their role during different developmental windows, from infancy to adulthood. For example, although laboratory rats are useful for studying juvenile social interactions, they are not ideal for studying infant attachment bonds. Here, we evaluate current understanding of the social behavior of Octodon degus, a diurnal precocial rodent, to elucidate the value of this species as a model for social-affective neuroscience research. After a synopsis of species-specific characteristics and brain susceptibility to changes of social environment, our behavioral findings on degu social proclivities are summarized. We then discuss why this pre-clinical model provides a valuable addition to the commonly available animal models for the study of human psychopathology.

机译：对社交情感神经科学计划的挑战是，要确定简单而有效的动物模型，以研究基本的社会情感表达及其在从婴儿期到成年期的不同发育期中的作用。例如，尽管实验室老鼠可用于研究青少年的社交互动，但对于研究婴儿依恋关系却不是理想的选择。在这里，我们评估当前对昼夜性啮齿类啮齿动物Octodon degus的社会行为的当前理解，以阐明该物种作为社会情感神经科学研究模型的价值。在概述了特定物种的特征和大脑对社会环境变化的敏感性之后，我们总结了关于degu社会倾向的行为发现。然后，我们讨论了为什么这种临床前模型为研究人类心理病理学的常用动物模型提供了有价值的补充。

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《Neuroscience and Biobehavioral Reviews》 |2011年第9期|共10页
作者
Colonnello V; Iacobucci P; Fuchs T; Newberry RC; Panksepp J;
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中图分类神经病学;
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1. Octodon degus. A useful animal model for social-affective neuroscience research: basic description of separation distress, social attachments and play. [J] . Colonnello V, Iacobucci P, Fuchs T, Neuroscience and Biobehavioral Reviews . 2011,第9期

机译：Octodon degus。用于社交情感神经科学研究的有用动物模型：分离困扰，社交依恋和游戏的基本描述。
2. Maternal separation followed by early social deprivation affects the development of monoaminergic fiber systems in the medial prefrontal cortex of Octodon degus. [J] . Braun K, Lange E, Metzger M, Neuroscience: An International Journal under the Editorial Direction of IBRO . 2000,第1期

机译：母体分离继之以早期的社会剥夺，影响了Octodon degus内侧前额叶皮层中单胺能纤维系统的发育。
3. Mother's voice "buffers" separation-induced receptor changes in the prefrontal cortex of octodon degus. [J] . Ziabreva I, Schnabel R, Poeggel G, Neuroscience: An International Journal under the Editorial Direction of IBRO . 2003,第2期

机译：母亲的声音“缓冲”了八角兽前额叶皮层中分离诱导的受体变化。
4. Social Neuroscience and the Study of Animal Communication [C] . Jakob Bro-J0rgensen Colloque médecine et recherche . 2014

机译：社会神经科学与动物沟通研究
5. An Examination of Executive Function, Stress, and Adolescent Attachment to Caregivers in a Social Neuroscience Model Using the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development (SECCYD). [D] . Brown, Margaux Hanes. 2014

机译：使用国家儿童健康与人类发展研究所（NICHD）的早期幼儿和青年发展研究（SECCYD），在社会神经科学模型中检查执行功能，压力和青少年对照顾者的依恋。
6. An Animal Model for Mammalian Attachment: Infant Titi Monkey (Plecturocebus cupreus) Attachment Behavior Is Associated With Their Social Behavior as Adults [O] . Logan E. Savidge, Karen L. Bales 2020

机译：哺乳动物依恋的动物模型：婴儿蒂蒂猴（Plecturocebus cupreus）的依恋行为与其成年后的社会行为有关
7. Early olfactory environment influences social behaviour in adult Octodon degus. [O] . Natalia Márquez, Jaime Martínez-Harms, Rodrigo A Vásquez, 2015

机译：早期嗅觉环境影响成年Octodon degus的社会行为。

Octodon degus. A useful animal model for social-affective neuroscience research: basic description of separation distress, social attachments and play.

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