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首页> 外文期刊>Neurosurgery >Primary intradural classic chondrosarcoma: case report and literature review.
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Primary intradural classic chondrosarcoma: case report and literature review.

机译：原发性硬膜内经典软骨肉瘤：病例报告及文献复习。

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OBJECTIVE AND IMPORTANCE: The exact origin of rare intradural chondrosarcomas remains obscure. We present a case report of an intradural classic chondrosarcoma (a very rare subtype of chondrosarcoma in this location), with a review of the literature, in an attempt to clarify the histogenesis of these tumors. CLINICAL PRESENTATION: A 48-year-old man presented with a 12-month history of progressive right hemiparesis. Computed tomography and magnetic resonance imaging demonstrated a left parietal space-occupying lesion. INTERVENTION: The patient underwent an image-guided, left parietal parasagittal craniotomy. An extrinsic tumor, which seemed to arise from the dura, was macroscopically removed. There was no bone involvement. The histological examination revealed a Grade II classic chondrosarcoma with tumor infiltration into the dura. Adjuvant radiotherapy was administered. CONCLUSION: Intradural chondrosarcomas are rare tumors, the majority of which are mesenchymal. Classic chondrosarcomas in this location are much rarer. Their histogenesis is uncertain. In this case, the origin seems to be from the dura. Because of the malignant potential of these tumors, radical extirpation whenever possible, followed by radiotherapy, is indicated.
机译：目的和重要性：罕见的硬膜内软骨肉瘤的确切来源仍然不清楚。我们提出了一种硬膜内经典软骨肉瘤（在此位置非常罕见的软骨肉瘤亚型）的病例报告，并结合文献进行了回顾，以试图阐明这些肿瘤的组织发生。临床表现：一名48岁男性患者，有进行性右半身轻瘫12个月的病史。计算机断层扫描和磁共振成像显示左顶空间占位性病变。干预：患者接受了影像引导的左顶矢状旁矢状开颅手术。肉眼观察到似乎是由硬脑膜引起的外源性肿瘤。没有骨骼受累。组织学检查显示有Ⅱ级经典软骨肉瘤，肿瘤浸润到硬脑膜。进行了辅助放疗。结论：硬膜内软骨肉瘤是罕见的肿瘤，大多数是间质的。在这个位置的经典软骨肉瘤很少见。它们的组织发生是不确定的。在这种情况下，起源似乎来​​自硬脑膜。由于这些肿瘤具有潜在的恶性，因此建议尽可能进行根治性根治，然后进行放射治疗。

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