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Adjustable Valves in Normal-pressure Hydrocephalus: A Retrospective Study of 218 Patients.

机译:常压性脑积水中的可调节瓣膜:218例患者的回顾性研究。

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OBJECTIVE: We sought to assess the value of adjusting shunt valve opening pressure, complications, and outcomes with the use of an adjustable shunt valve in the treatment of patients with normal-pressure hydrocephalus (NPH). METHODS: In a single-center retrospective study, 231 adjustable valves (range, 30-200 mm H(2)O) were the first shunt implantations in 147 patients with idiopathic NPH (INPH) and 71 patients with secondary NPH (SNPH). The effect of adjustment on gait disturbance, cognitive impairment, urinary incontinence and other symptoms were evaluated, and an improvement index was created. RESULTS: In the INPH group, 138 adjustments were performed in 49.0% of the patients (average, 0.94 adjustments/patient). For the SNPH group, 49 adjustments were performed in 32.4% of the patients (average, 0.69 adjustments/patient). The reasons for adjustment were overdrainage in 48 patients (25.7%), underdrainage in 98 patients (52.4%), subdural hematoma in 37 patients (19.8%), and other reasons in 2 patients(2.1%). Clinical status improved after 56 (49.1%) of all 114 adjustments, whereas 23 (42.6%) of 54 minor (
机译:目的:我们试图评估使用可调式分流阀治疗常压性脑积水(NPH)患者的价值。方法:在单中心回顾性研究中,对147例特发性NPH(INPH)和71例继发性NPH(SNPH)患者进行了首次分流植入,其中有231个可调节瓣膜(范围为30-200 mm H(2)O)。评估了调整对步态障碍,认知障碍,尿失禁和其他症状的影响,并建立了改善指标。结果:在INPH组中,对49.0%的患者进行了138次调整(平均,每名患者0.94调整)。对于SNPH组,在32.4%的患者中进行了49次调整(平均每位患者0.69调整)。调整的原因是引流过多的48例(25.7%),引流不足的98例(52.4%),硬膜下血肿37例(19.8%),以及其他原因2例(2.1%)。全部114项调整中有56项(49.1%)改善了临床状态,而54项较小(

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