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首页> 外文期刊>Neurosurgery >Intraoperative Ultrasound Using Phase Inversion Harmonic Imaging: First Experiences
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Intraoperative Ultrasound Using Phase Inversion Harmonic Imaging: First Experiences

机译：使用相位反转谐波成像术中超声：第一次经验。

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OBJECTIVE:To study the feasibility of inlraoperative ultrasound using the phase inversion harmonic imaging (PIHI) technique. METHODS: Fight patients wilh intracranial middle cerebral artery aneurysms and five patients with arleriovenous malformations were studied after written informed consent. A first ultrasound study was performed through the intact dura mater after cranial trepanation to assess the pathology, its feeding artery, and downstream segments. A second ultrasound study was performed immedialelv after intervention to monitor the success of the procedure. All patients were studied using a Siemens Sonoline Antares ultrasound machine (Siemens Medical Solutions USA, Inc., Malvern, PA) before and after intravenous administration of an ultrasound contrast agent (Optison; GF Healthcare, Milwaukee, VYI.i. Other than conventional brightness mode;, PIHI is sensitive to the nonlinear acoustic response1 of tissue1, and especially to ultrasound contrast agent mkrobub-bles. The latter enables contrast-specific vascular imaging. RESULTS: Pll II provided anatomically detailed information. In combination wilh an ultrasound contrast agent, angiography-like views of the vascular pathologies, inc lud-ing their surrounding vessels, could be obtained. Flow velocities in afferent and downstream vascular segments, as well as inside the pathology, could be assessed. How dynamics inside the aneurysm sac or the arteriovenous malformation could be studied in real-time. Postintervention, contrast-enhanced PIHI could be used to immediately monitor the1 success of the surgical procedure. CONCLUSION: PIHI enables intraoperative visualization and morphological assessment of neurovascular pathologies, such as middle cerebral artery aneurysms or arleriovenous malformations. In combination with an ultrasound contrast agent, the flow-dynamics of these lesions can be displayed in real-time.
机译：目的：利用倒相谐波成像（PIHI）技术研究术中超声检查的可行性。方法：经过书面知情同意后，研究了颅内中动脉瘤的搏斗患者和五例静脉曲张畸形的患者。头颅超声检查是在颅骨切开后通过完整的硬脑膜进行的，以评估其病理学，其进食动脉和下游节段。干预后立即进行第二次超声研究以监测手术的成功。在静脉内施用超声造影剂（Optison; GF Healthcare，密尔沃基，VYI.i）之前和之后，均使用Siemens Sonoline Antares超声仪（Siemens Medical Solutions USA，Inc.，宾夕法尼亚州，马尔文）对所有患者进行了研究，常规亮度除外模式; PIHI对组织1的非线性声学响应1敏感，特别是对超声造影剂mkrobub-bles敏感，后者可以进行造影剂特异性血管成像。结果：Pll II提供了解剖学上详细的信息。可以获得包括周围血管在内的类似血管造影的视图，可以评估传入和下游血管段以及病理内部的流速，以及动脉瘤囊或动静脉内部的动态干预后，可使用对比增强的PIHI来立即监测t的成功率。他的手术程序。结论：PIHI可进行术中可视化和神经血管病理学形态评估，例如大脑中动脉瘤或动脉静脉畸形。结合超声造影剂，可以实时显示这些病变的血流动力学。

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