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首页> 外文期刊>Neurosurgery >Implementation of dual simultaneous microelectrode recording systems during deep brain stimulation surgery for Parkinson's disease: technical note.
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Implementation of dual simultaneous microelectrode recording systems during deep brain stimulation surgery for Parkinson's disease: technical note.

机译:在帕金森氏病深部脑刺激手术中实施双同时微电极记录系统:技术说明。

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OBJECTIVE: Microelectrode recording during deep brain stimulation surgery improves the likelihood of successful target localization and enables the electrophysiological characterization of human neural structures. Many clinical recording systems do not support the ability to capture research-quality recordings. Established clinical centers already using such equipment may be prevented from acquiring human intracranial data because of the need to completely change recording systems to obtain research-quality recordings. This technical note describes the novel design and implementation of a recording system that significantly improves research capabilities without disrupting the existing clinical setup. METHODS: This design introduces a second recording system (including pre-amplifier, differential amplifier, analog-to-digital converter, and computer with analysis software) that divides the microelectrode signal into two independent streams. RESULTS: This design preserves the existing intraoperative recording setup, but significantly improves research-level recording, data storage, and analysis capabilities. CONCLUSION: We provide the first description of such a system using components that are all commercially available and relatively inexpensive. This approach presents an appealing alternative to the purchase of an entirely new system for surgical teams that already perform intraoperative recordings to assist in stereotactic target localization, yet wish to expand their neurophysiological recording capabilities.
机译:目的:在深部脑刺激手术中记录微电极可提高成功定位靶标的可能性,并能对人的神经结构进行电生理学表征。许多临床记录系统不支持捕获具有研究质量的记录的功能。由于需要完全更改记录系统以获得研究质量的记录,因此可能会阻止已经在使用此类设备的已建立临床中心获取人类颅内数据。本技术说明介绍了记录系统的新颖设计和实现,该系统可以在不中断现有临床设置的情况下显着提高研究能力。方法:本设计引入了第二种记录系统(包括前置放大器,差分放大器,模数转换器和带有分析软件的计算机),该系统将微电极信号分为两个独立的流。结果:该设计保留了现有的术中记录设置,但显着提高了研究水平的记录,数据存储和分析能力。结论:我们提供了这样一个系统的首次描述,该系统使用的组件都是可商购的并且相对便宜。这种方法为购买已经进行了术中记录以协助立体定向目标定位但希望扩展其神经生理学记录功能的外科团队购买全新系统提供了一种有吸引力的选择。

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