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Measuring clinical practice: Science and methods

机译:衡量临床实践:科学与方法

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摘要

The routine practice of neurosurgery generates a large amount of clinical data. The structured, systematic capture of this information using clinical registries or other rigorously designed observational studies can yield useful evidence to help improve the care of patients. Registries in particular can be designed to measure outcomes in realworld clinical settings and to study differences in outcomes between subgroups. This information can help clinicians to advise patients regarding their treatment options. To provide valid, generalizable evidence, however, registries and other observational studies must be designed and conducted with a rigor similar to that of randomized clinical trials. Neurosurgeons with a basic understanding of the potential advantages and pitfalls of nonrandomized trials and the methods of statistical analysis will be able to assess the quality of clinical data and to incorporate the findings appropriately into their patients' care.
机译:神经外科的常规做法产生了大量的临床数据。使用临床注册表或其他经过严格设计的观察性研究对这些信息进行结构化,系统的捕获,可以提供有用的证据来帮助改善患者的护理。特别是可以设计注册表来衡量现实世界中临床结果的结果,并研究亚组之间结果的差异。这些信息可以帮助临床医生就治疗方案向患者提供建议。但是,为了提供有效的,可概括的证据,必须以与随机临床试验相似的严格性设计和进行注册表和其他观察性研究。基本了解非随机试验的潜在优势和陷阱以及统计分析方法的神经外科医师将能够评估临床数据的质量,并将发现适当地纳入患者的护理中。

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