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首页> 外文期刊>journal of clinical and diagnostic research >Vitamin D Deficiency in Children with Chronic Kidney Disease
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Vitamin D Deficiency in Children with Chronic Kidney Disease

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Vitamin D deficiency leads to defective mineralisation and in Chronic Kidney Disease (CKD) can contribute to renal osteodystrophy.Aim: To compare the serum level of vitamin D in children with CKD as compared to those with normal condition.Materials and Methods: This cross-sectional survey was performed on 68 consecutive children with CKD and 73 sex and age-matched healthy children who were referred to Mofid hospital in Tehran, Iran in 2016. Serum level of vitamin D was measured by immunoassay kits and was then categorised as =15 ng/dL (for vitamin D deficiency), 16-30 ng/dL (for vitamin D insufficiency) and >30 ng/dL (for normal condition). Also, the CKD stage was determined by measuring estimated Glomerular Filtration Rate (GFR). Quantitative variables were compared with the t-test, Mann-Whitney test, ANOVA test, or Kruskal-Wallis H test. Qualitative variables were also compared with chi-square test or Fisher’s-exact test.Results: Comparing serum level of vitamin D between CKD and control group showed a significant difference (14.3±9.8 ng/mL versus 18.3±10.9 ng/mL, pConclusion: Vitamin D deficiency is a common problem among children with CKD compared to control group. In CKD patients vitamin D level is decreased with increasing CKD stage.

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