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首页> 外文期刊>Biochemistry >Relationship between Contents of Lipocalin-Type Prostaglandin D Synthase on the Surface of Infertility Sperm and in Seminal Plasma
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Relationship between Contents of Lipocalin-Type Prostaglandin D Synthase on the Surface of Infertility Sperm and in Seminal Plasma

机译:不育精液表面脂精蛋白型前列腺素D合酶含量与精浆中血浆之间的关系

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摘要

Lipocalin-type prostaglandin D synthase(L-PGDS)is localized in Leydig cells,sperm,and epithelial cells of the epididymis.The present study was to determine the correlation between content of this enzyme in seminal plasma and on the surface of sperm.We analyzed 90 semen samples.L-PGDS in seminal plasma was analyzed by an ELISA procedure.L-PGDS on sperm was analyzed by flow cytometry.The semen donors were categorized in three groups:normal,oligosper-mic,and azoospermic.According to results obtained,L-PGDS may have the ability to improve progressive motility of sperm,and L-PGDS in seminal plasma and on sperm surface may impact male fertility in the female reproductive tract.
机译:脂蛋白素型前列腺素D合酶(L-PGDS)位于附睾的Leydig细胞,精子和上皮细胞中。本研究旨在确定精浆中该酶含量与精子表面之间的相关性。分析了90个精液样本,通过ELISA方法分析了精浆中的L-PGDS,通过流式细胞仪分析了精子上的L-PGDS,将精子供体分为正常,少精子和无精子三类。 L-PGDS可能具有改善精子进行性的能力,精液中和精子表面的L-PGDS可能会影响女性生殖道的男性生育能力。

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