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首页> 外文期刊>Nordic journal of psychiatry. >Cognitive behavior therapy for schizophrenia: a meta-analytical review of randomized controlled trials.
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Cognitive behavior therapy for schizophrenia: a meta-analytical review of randomized controlled trials.

机译：精神分裂症的认知行为疗法：一项随机对照试验的荟萃分析综述。

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BACKGROUND: In the UK and in Sweden, cognitive behavior therapy (CBT) has been recommended for schizophrenia. The two recent meta-analyses examined results soon after treatment and not at follow-up. AIM: To determine the effectiveness of CBT in people with schizophrenia, both after treatment and at follow-up, and to compare it with treatment as usual (TAU) and other psychological treatments. METHODS: The search was carried in the databases CENTRAL (Cochrane Central Register of Controlled Trials), PsycINFO and PubMed (Medline). Inclusion criteria were randomized controlled trials (RCTs) with low risk of bias. Two reviewers, working independently, extracted data. The results were analyzed using risk ratio (RR), risk difference (RD), mean difference (MD), or standardized mean difference (SMD). Outcome measures were symptoms, use of medication, relapse and clinically important improvement. RESULTS: When CBT was compared with other psychological treatments at follow-up, there was strong evidence (with small treatment effect) that intervention has an effect with positive symptoms (P = 0.02), negative symptoms (P = 0.03) and general symptoms (P = 0.003). After treatment, there was a trend in favor of CBT, but not statistically significantly so. CONCLUSION: It appears that the effect of CBT is delayed; it could be seen a few months after the treatment had terminated. Therapies for patients with schizophrenia that were 20 sessions long or more had better outcomes than those that were shorter.
机译：背景：在英国和瑞典，已建议对精神分裂症进行认知行为疗法（CBT）。最近的两项荟萃分析在治疗后而非随访时检查了结果。目的：确定CBT在精神分裂症患者治疗后和随访中的有效性，并将其与常规治疗（TAU）和其他心理治疗进行比较。方法：该搜索在数据库CENTRAL（对照试验的Cochrane中央登记册），PsycINFO和PubMed（Medline）中进行。纳入标准为偏倚风险低的随机对照试验（RCT）。两名独立工作的审阅者提取了数据。使用风险比（RR），风险差异（RD），平均差异（MD）或标准化平均差异（SMD）分析结果。结果指标包括症状，药物使用，复发和临床上重要的改善。结果：在随访中将CBT与其他心理治疗进行比较时，有强有力的证据（治疗效果很小）表明干预措施具有阳性症状（P = 0.02），阴性症状（P = 0.03）和一般症状（P = 0.02）。 P = 0.003）。治疗后，有支持CBT的趋势，但统计学上没有明显趋势。结论：看来CBT的作用被延迟了。可以在治疗终止几个月后看到。持续时间超过20个疗程的精神分裂症患者的治疗效果优于短期治疗。

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