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A nested case-control study of the risk of suicide attempts after discharge from psychiatric care: the role of co-morbid substance use disorder.

机译:一项嵌套的病例对照研究,涉及精神病护理出院后自杀未遂的风险:共病物质使用障碍的作用。

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摘要

The literature suggests that the risk of suicide is high within the first weeks after discharge from psychiatric care, but practically no studies have estimated the risk of suicide attempt after discharge from psychiatric care. The aim of this study was to examine the risk level for suicide attempt after discharge from psychiatric care, and to control for effects from psychiatric diagnoses, number and length of previous admission. An analysis of the role of co-morbid substance use disorder in suicide attempts risk was completed. The study is a Danish register-based nested case-control study; 3037 cases were identified from Register for Suicide Attempts, and 60,295 individuals, matched by gender and age, were identified for comparison. Retrospective personal data on psychiatric care was obtained from the Danish Psychiatric Central Register. Risk of suicide attempts was estimated by the use of conditional logistic regression. We found a significant high peak in risk of suicide attempts in the first weeks after discharge from psychiatric care. The risk was lowered as time passed by. Suicide attempt risk was not equally distributed across various psychiatric diagnoses, and co-morbidity of substance abuse with mental illness raised risk in an additive way. We found only small gender differences in risk. In order to lower the risk of suicide attempts, we need to improve after-care when discharging from psychiatric care. A differentiation between the possibilities of after-care for different mental illnesses is needed.
机译:文献表明,精神病护理出院后的最初几周内自杀的风险很高,但实际上没有研究评估精神病护理出院后自杀未遂的风险。这项研究的目的是检查从精神病治疗出院后自杀未遂的风险水平,并控制精神病诊断的影响,先前入院的次数和时间。共病物质使用障碍在自杀未遂风险中的作用的分析已完成。该研究是丹麦基于登记册的嵌套病例对照研究。从自杀未遂登记簿中确认了3037例病例,并确定了60295例按性别和年龄匹配的个体进行比较。有关精神病治疗的回顾性个人数据是从丹麦精神病学中央登记处获得的。通过使用条件逻辑回归来估计自杀未遂的风险。我们发现,出院后的头几周自杀未遂风险很高。随着时间的流逝,风险降低了。自杀未遂风险在各种精神病学诊断中分布不均,药物滥用与精神疾病的合并发病率以累加方式增加了风险。我们发现风险中的性别差异很小。为了降低自杀未遂的风险,从精神病治疗出院后,我们需要改善后期护理。需要区别对待不同精神疾病的可能性。

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