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首页> 外文期刊>Nordic journal of psychiatry. >Testing the cognitive effort hypothesis of cognitive impairment in major depression.
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Testing the cognitive effort hypothesis of cognitive impairment in major depression.

机译：测试重度抑郁症认知障碍的认知努力假设。

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摘要

BACKGROUND: It is widely accepted that depression is associated with deficits in a range of cognitive domains. However, there is no consensus regarding the neuropsychological profile in depression. AIM: The aim of the present report is to test the cognitive effort hypothesis as a possible framework for understanding the observed cognitive impairment in major depressive disorder (MDD), using the Delis Kaplan Executive Function system (D-KEFS). METHOD: Twenty-four patients with recurrent MDD, in the acute phase of illness, were compared with a healthy control group. We expected that the patient group would show impairment on tests that measure higher-level effortful cognitive processing, whereas basic cognitive skills would be equal to the control group. RESULTS: There were no differences between the two groups on measures of basic cognitive skills, except for Colour Naming. Furthermore, MDD patients performed significantly worse than the control group on three out of seven of the cognitively effortful measures; namely Inhibition, Inhibition/Switching and Category Fluency. CONCLUSIONS: We could not find consistent support for the cognitive effort hypothesis in the present study. However, the results indicate that depressed patients have a specific impairment within the Executive Function domain affecting Inhibition, Inhibition/Switching and Category Fluency.
机译：背景：人们普遍认为抑郁症与一系列认知领域的缺陷有关。但是，关于抑郁症的神经心理特征尚无共识。目的：本报告的目的是使用Delis Kaplan执行功能系统（D-KEFS）来测试认知努力假设，将其作为了解在重度抑郁症（MDD）中观察到的认知障碍的可能框架。方法：将二十四位在疾病急性期复发的MDD患者与健康对照组进行比较。我们期望患者组在测试更高级别的努力性认知过程的测试中会表现出障碍，而基本认知技能将与对照组相同。结果：除了颜色命名外，两组在基本认知技能的测量上没有差异。此外，在七分之三的认知努力措施中，MDD患者的表现明显比对照组差;即抑制，抑制/转换和类别流畅性。结论：在本研究中，我们找不到对认知努力假设的一致支持。但是，结果表明，抑郁症患者在执行功能域内有特定的障碍，影响抑制，抑制/转换和类别流畅性。

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