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首页> 外文期刊>Nordic journal of psychiatry. >Alcohol use and psychiatric comorbid disorders predict deliberate self-harm behaviour and other suicidality among depressed adolescent outpatients in 1-year follow-up
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Alcohol use and psychiatric comorbid disorders predict deliberate self-harm behaviour and other suicidality among depressed adolescent outpatients in 1-year follow-up

机译：酗酒和精神病合并症可预测1年随访中青春期抑郁门诊患者的故意自残行为和其他自杀倾向

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Background: Suicidality, including deliberate self-harm behaviour (DSH), represents one of the most adverse and clinically serious consequences of depression. More detailed longitudinal research is needed in order to find clinical risk factors of DSH and other suicidal behaviour among depressed adolescent outpatients in order to identify those at greatest risk of life-threatening behaviour. Aim: This follow-up study investigated alcohol use, Axis I comorbid disorders, depressive and anxiety symptoms, and psychosocial functioning as risk factors of suicidal behaviour, including DSH, among depressed adolescent outpatients during a 1-year follow-up. Methods: Consecutive depressed adolescent outpatients (n 189) aged 1319 years were interviewed at baseline and at follow-up by using the Schedule for Affective Disorders and Schizophrenia for School-Aged ChildrenPresent and Lifetime (K-SADS-PL) for DSM-IV Axis I diagnoses and self-report questionnaires. Suicidal behaviour was assessed by K-SADS suicidality items. Results: During 1-year follow-up, one-quarter of all participants, and almost three-quarters of suicidal adolescents had DSH. Alcohol use and mood disorder with Axis I comorbidity at baseline predicted both DSH and other suicidal behaviour during follow-up. Mood disorder during follow-up predicted all forms of suicidal behaviour. Conclusions: Detection and effective treatment of continuing mood disorder, comorbid disorders and alcohol use may significantly improve clinician's ability to identify adolescent outpatients at high risk of subsequent DSH and other suicidal behaviour. Treatment interventions should aim at full recovery of depression.
机译：背景：包括故意的自残行为（DSH）在内的自杀倾向是抑郁症最不利和临床上最严重的后果之一。需要进行更详细的纵向研究，以便在抑郁的青少年门诊患者中发现DSH和其他自杀行为的临床危险因素，从而确定那些威胁生命的行为风险最大的人。目的：这项随访研究调查了抑郁症青少年门诊患者在1年的随访中饮酒，I轴合并症，抑郁和焦虑症状以及心理社会功能等自杀行为危险因素（包括DSH）的情况。方法：采用DSM-IV Axis的“学龄前儿童情感障碍和精神分裂症现况和终生（K-SADS-PL）”，在基线和随访时对1319岁的连续抑郁青少年门诊患者（n 189例）进行基线和随访。我诊断并自我报告调查表。通过K-SADS自杀项目评估自杀行为。结果：在1年的随访中，所有参与者的四分之一和自杀性青少年的近四分之三患有DSH。基线时I轴合并症的饮酒和情绪障碍预示了随访期间的DSH和其他自杀行为。随访期间的情绪障碍预示了所有形式的自杀行为。结论：对持续性情绪障碍，合并症和酗酒的检测和有效治疗可能会显着提高临床医生识别具有后续DSH和其他自杀行为高风险的青少年门诊病人的能力。治疗干预措施应旨在使抑郁症完全康复。

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