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首页> 外文期刊>Nutrition & Food Science >Effects of konjac glucomannan hydrolysates on the gut microflora of mice.
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Effects of konjac glucomannan hydrolysates on the gut microflora of mice.

机译：魔芋葡甘露聚糖水解物对小鼠肠道菌群的影响。

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摘要

Effects of depolymerized mannans and specifically konjac glucomannan hydrolysates (GMH) on the colonic microflora of mice were examined. Blood glucose and cholesterol were also measured. 2 groups (n = 20) of 12-wk old Wister mice were used for a period of 14 wk. 1 group (treatment group) were fed diets containing 5% konjac GMH dissolved in drinking water in addition to the control (group) standard diet. Faecal microflora, feed consumption, body wt., blood glucose and cholesterol were determined. Results showed that the GMH promoted the growth of anaerobes and lactobacilli in the treatment group (P < 0.001). Also, the hydrolysate was able to significantly reduce (P < 0.001) faecal Clostridium perfringens and Escherichia coli counts. A significant increase in average daily feed consumption (P < 0.05) and weekly body wt. (P < 0.001) was found for the treatment group. The mean +or- s.d. (mmol/l) of blood glucose and cholesterol was lower in the treatment group. Although this needs to be verified by further studies, it is suggested that GMH could also be a candidate for possible treatment of subjects with high cholesterol and for diabetics.
机译：检查了解聚的甘露聚糖，特别是魔芋葡甘露聚糖水解物（GMH）对小鼠结肠菌群的影响。还测量了血糖和胆固醇。使用2组（n = 20）的12周龄Wister小鼠，持续14周。 1组（治疗组）除对照组（组）标准饮食外，还添加了溶于饮用水的5％魔芋GMH饮食。测定粪便微生物区系，饲料消耗，体重，血糖和胆固醇。结果显示，GMH促进了治疗组厌氧菌和乳酸菌的生长（P <0.001）。而且，水解产物能够显着减少（P <0.001）粪便产气荚膜梭状芽胞杆菌和大肠杆菌计数。平均每日饲料消耗量（P <0.05）和每周体重显着增加。发现治疗组（P <0.001）。平均值+或d。治疗组的血糖和胆固醇水平（mmol / l）较低。尽管这需要通过进一步的研究加以验证，但建议GMH也可以作为可能治疗高胆固醇受试者和糖尿病患者的候选药物。

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