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Fruit and vegetable intake and risk of wheezing and asthma: A systematic review and meta-analysis

机译:水果和蔬菜的摄入量及喘息和哮喘的风险:系统评价和荟萃分析

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摘要

Major bibliographic databases were searched for studies examining the relationship between fruit and vegetable consumption and the risk of wheezing and asthma. Random-effects models were used to pool study results. Subgroup analyses were conducted by fruit and vegetable categories, study design, and age group. Twelve cohorts, 4 population-based case-control studies, and 26 cross-sectional studies published between January 1990 and July 2013 were identified. For the meta-analysis of adults and children, the relative risk (RR) and confidence intervals (CI) when comparing the highest intake group with the lowest intake group were 0.78 (95%CI, 0.70-0.87) for fruit and 0.86 (95%CI, 0.75-0.98) for vegetables. High intake of fruit and vegetables (RR=0.76; 95%CI, 0.68-0.86 and RR=0.83; 95%CI, 0.72-0.96) reduced the risk of childhood wheezing. Total intake of fruit and vegetables had a negative association with risk of asthma in adults and children (RR = 0.54; 95%CI, 0.41-0.69). Consuming fruit and vegetables during pregnancy had no association with the risk of asthma in offspring. High intake of fruit and vegetables may reduce the risk of asthma and wheezing in adults and children.
机译:检索了主要的书目数据库,以研究水果和蔬菜的摄入量与喘息和哮喘风险之间的关系。随机效应模型用于汇总研究结果。按水果和蔬菜类别,研究设计和年龄组进行亚组分析。确定了1990年1月至2013年7月发表的12项队列研究,4项基于人群的病例对照研究以及26项横断面研究。对于成人和儿童的荟萃分析,比较最高摄入量组和最低摄入量组时,水果的相对风险(RR)和置信区间(CI)为0.78(95%CI,0.70-0.87)和0.86(95)蔬菜的%CI,0.75-0.98)。大量摄入水果和蔬菜(RR = 0.76; 95%CI,0.68-0.86和RR = 0.83; 95%CI,0.72-0.96)降低了儿童喘息的风险。成人和儿童中,水果和蔬菜的总摄入量与哮喘风险呈负相关(RR = 0.54; 95%CI,0.41-0.69)。怀孕期间食用水果和蔬菜与后代患哮喘的风险无关。大量摄入水果和蔬菜可以降低成人和儿童患哮喘和喘息的风险。

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