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Self-organized and highly ordered domain structures within swarms of Myxococcus xanthus.

机译:黄花粘球菌群内的自组织和高度有序的域结构。

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摘要

Coordinated group movement (swarming) is a key aspect of Myxococcus xanthus' social behavior. Here we report observation of domain structures formed by multiple cells within large three-dimensional swarming groups grown on amorphous glass substrates, using the atomic force microscope (AFM). Novel analyses revealed that 90% of the wild type swarms displayed some form of preferential cell alignment. In contrast, cells with mutations in the social and adventurous motility systems displayed a distinct lack of cell alignment. Video microscopy observations of domain features of in vivo swarming M. xanthus cells were also consistent with the AFM data. The results presented here reveal that unique domain formation within swarms of wild type cells is a biologically driven process requiring the social and adventurous motility systems and is not a statistical phenomenon or thermodynamic process arising from liquid crystal behavior.
机译:协调运动(群策群力)是黄色粘球菌社会行为的关键方面。在这里,我们报告使用原子力显微镜(AFM)观察在非晶玻璃基板上生长的大型三维群中多个单元形成的畴结构。新颖的分析表明,90%的野生型种群表现出某种形式的优先细胞排列。相反,在社交和冒险运动系统中具有突变的细胞表现出明显的细胞排列缺乏。视频显微镜观察到的体内群虫黄单胞菌细胞的域特征也与AFM数据一致。此处显示的结果表明,野生型细胞群内独特的结构域形成是生物驱动的过程,需要社会和冒险的运动系统,而不是液晶行为引起的统计现象或热力学过程。

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