KINESIN-ASSOCIATED TRANSPORT IS INVOLVED IN THE REGULATION OF CELL ADHESION

Kaverina IN.; Gyoeva FK.; Vasiliev JM.; Minin AA.

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KINESIN-ASSOCIATED TRANSPORT IS INVOLVED IN THE REGULATION OF CELL ADHESION

机译：驱动蛋白相关的运输参与细胞粘附的调控。

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It has been recently shown that depolymerization of microtubules induces the elongation of focal contacts at the leading edge. On the other hand, cell shape and pseudopodial activity were found to depend on the microtubule-based motor kinesin. In this paper, we examine whether kinesin is involved in controlling the dynamics of adhesive structures at the cell surface. Microinjection of an antiblocking kinesin activity in vitro causes focal contact elongation similar to the effect of microtubule-depolymerizing drugs. Thus, the role of microtubules in cell adhesion lies in the supporting kinesin-based transport to the adhesion sites. (C) 1997 Academic Press Limited. [References: 16]

机译：最近已经表明，微管的解聚引起前缘焦点接触的伸长。另一方面，发现细胞形状和假足活性取决于基于微管的运动驱动蛋白。在本文中，我们检查驱动蛋白是否参与控制细胞表面黏附结构的动力学。在体外显微注射抗封闭驱动蛋白活性会引起局部接触伸长，类似于微管解聚药物的作用。因此，微管在细胞粘附中的作用在于基于驱动蛋白的向粘附部位的转运。（C）1997 Academic Press Limited。 [参考：16]

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《Cell biology international.》 |1997年第4期|共8页
作者
Kaverina IN.; Gyoeva FK.; Vasiliev JM.; Minin AA.;
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正文语种 eng
中图分类细胞生物学;
关键词
Focal adhesions; Kinesin; Microtubules; Intermediate filaments; Fibroblasts; Shape; Microtubules;

机译：局灶性黏附;动力蛋白;微管;中间丝;成纤维细胞;形状;微管;

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1. KINESIN-ASSOCIATED TRANSPORT IS INVOLVED IN THE REGULATION OF CELL ADHESION [J] . Kaverina IN., Gyoeva FK., Vasiliev JM., Cell biology international. . 1997,第4期

机译：驱动蛋白相关的运输参与细胞粘附的调控。
2. CD166/Activated leukocyte cell adhesion molecule is expressed on glioblastoma progenitor cells and involved in the regulation of tumor cell invasion [J] . Noriyuki Kijima, Naoki Hosen, Naoki Kagawa, Neuro-Oncology . 2012,第10期

机译：CD166 /活化的白细胞粘附分子在胶质母细胞瘤祖细胞上表达并参与肿瘤细胞侵袭的调控
3. Extracellular transglutaminase 2 has a role in cell adhesion, whereas intracellular transglutaminase 2 is involved in regulation of endothelial cell proliferation and apoptosis. [J] . Nadalutti C, Viiri KM, Kaukinen K, Cell Proliferation . 2011,第1期

机译：细胞外转谷氨酰胺酶2在细胞黏附中起作用，而细胞内转谷氨酰胺酶2参与内皮细胞增殖和凋亡的调节。
4. Structure-function relationships of the di/tri-peptide transporter of the yeast Saccharomyces cerevisiae:a model system for studying substrate recognition and regulation of membrane proteins involved in peptide transport [C] . Jeffrey M.Becker, Melinda Hauser, Steven Minkin International Peptide Symposium;European Peptide Symposium . 2005

机译：酵母酿酒酵母的DI /三肽转运蛋白的结构函数关系：一种研究底物识别的模型系统和肽运输中膜蛋白的调节
5. Novel mechanisms of regulation of the Cdc42 GTPase-activating protein CdGAP/ARHGAP31, a protein involved in cell migration and adhesion. [D] . Primeau, Martin. 2011

机译：调节Cdc42 GTPase活化蛋白CdGAP / ARHGAP31的新机制，该蛋白参与细胞迁移和粘附。
6. CFTR Cl– channel functional regulation by phosphorylation of focal adhesion kinase at tyrosine 407 in osmosensitive ion transporting mitochondria rich cells of euryhaline killifish [O] . William S. Marshall, Kaitlyn D. Watters, Leah R. Hovdestad, -1

机译：CFTR Cl–通道功能调节渗透敏感离子中酪氨酸407上的粘着斑激酶磷酸化运送富含线粒体的鱼腥藻双歧杆菌细胞
7. CD166/Activated leukocyte cell adhesion molecule is expressed on glioblastoma progenitor cells and involved in the regulation of tumor cell invasion [O] . N. Kijima, N. Hosen, N. Kagawa, 2011

机译：CD166 /活化的白细胞粘附分子在胶质母细胞血浆细胞上表达并参与肿瘤细胞侵袭的调节

KINESIN-ASSOCIATED TRANSPORT IS INVOLVED IN THE REGULATION OF CELL ADHESION

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