CENTROSOME BEHAVIOUR AND ORIENTATION OF CENTRIOLES UNDER THE ACTION OF ENERGY TRANSFER INHIBITORS

Alieva IB; Vorobjev IA

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CENTROSOME BEHAVIOUR AND ORIENTATION OF CENTRIOLES UNDER THE ACTION OF ENERGY TRANSFER INHIBITORS

机译：在能量转移抑制剂的作用下质心的行为和取向

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2,4-dinitrophenol, dinitrophenol together with deoxyglucose, sodium azide and ouabain didn't alter cytoplasmic microtubule (MT) network of cultured PK (pig kidney embryo) cells, meanwhile they induced an increase in the average number of pericentriolar satellites and percentage of centrioles with the primary cilium in these cells. Also all drugs studied increase number of MTs attached to and oriented towards the centrosome. Under the action of ouabain the total number of MTs around the centrosome doubled, meanwhile the number of long MTs emanating from the centrosome increased more than 15 times. Under the action of all drugs studied, except sodium azide, the number of maternal centrioles oriented perpendicularly to the substrate surface increased significantly from that in control cells.

机译：2,4-二硝基苯酚，二硝基苯酚以及脱氧葡萄糖，叠氮化钠和哇巴因并没有改变培养的PK（猪肾胚胎）细胞的细胞质微管（MT）网络，同时它们诱导了平均周围小卫星的数量和百分比的增加。这些细胞中带有初级纤毛的中心粒。同样，所有研究的药物都增加了附着并定向于中心体的MT数量。在哇巴因的作用下，中心体周围的MT总数增加了一倍，而从中心体发出的长MT数量增加了15倍以上。在所有研究的药物（叠氮化钠除外）的作用下，垂直于底物表面的母体中心粒的数量比对照细胞中的数量显着增加。

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《Cell biology international.》 |1995年第2期|共10页
作者
Alieva IB; Vorobjev IA;
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正文语种 eng
中图分类细胞生物学;
关键词
Centriole; Centrosome; Energy transfer inhibitors; Microtubules; Microtubules; Organization; Uncoupler; Invitro; Cells;

机译：离心;中心体;能量转移抑制剂;微管;微管;组织;解偶联剂;体外;细胞;

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1. CENTROSOME BEHAVIOUR AND ORIENTATION OF CENTRIOLES UNDER THE ACTION OF ENERGY TRANSFER INHIBITORS [J] . Alieva IB, Vorobjev IA Cell biology international. . 1995,第2期

机译：在能量转移抑制剂的作用下质心的行为和取向
2. Discovery of kinase inhibitors by high-throughput docking and scoring based on a transferable linear interaction energy model [J] . Kolb P, Huang D, Dey F, Journal of Medicinal Chemistry . 2008,第5期

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3. Switching of energy transfer reaction by the control of orientation factor between porphyrin derivatives on the clay surface [J] . Miharu Eguchi, Yo Watanabe, Yuta Ohtani Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2014,第16期

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4. Nanomolecular gravitational interactions causing increased probability of birth defects in humans during period from conception to early fetus formation - induced change in centriole separation and consequent probability for disadvantageous mutation [C] . G. C. Vezzoli International Conference on Computational Nanoscience and Nanotechnology . 2002

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5. The centrosome: Identification of new components, a study of behaviour, and its role in human autoimmune disease. [D] . Mack, Gary James. 1999

机译：中心体：新成分的鉴定，行为及其在人类自身免疫性疾病中的作用的研究。
6. Some behavioural and anticonvulsant actions in mice of ethanolamine O-sulphate an inhibitor of 4-aminobutyrate aminotransferase. [O] . M G Baxter, L J Fowler, A A Miller, 1973

机译：乙醇胺O-硫酸盐（4-氨基丁酸氨基转移酶的抑制剂）在小鼠中的某些行为和抗惊厥作用。
7. Centrosome behaviour and orientation of centrioles under the action of energy transfer inhibitors [O] . I. B. Alieva, I. A. Vorobjev 1995

机译：中心体在能量转移抑制剂作用下的行为和中心体的取向

CENTROSOME BEHAVIOUR AND ORIENTATION OF CENTRIOLES UNDER THE ACTION OF ENERGY TRANSFER INHIBITORS

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