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Substance abuse, adherence with antiretroviral therapy, and clinical outcomes among HIV-infected individuals.

机译:艾滋病毒感染者的药物滥用,坚持抗逆转录病毒疗法以及临床结果。

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摘要

Substance abuse and addiction are highly prevalent in HIV-infected individuals. Substance abuse is an important comorbidity that affects the delivery and outcomes of HIV medical management. In this paper I will review data examining the associations between substance abuse and HIV treatment and potential strategies to improve outcomes in this population that warrant further investigation. Current - but not past - substance abuse adversely affects engagement in care, acceptance of antiretroviral therapy, adherence with therapy, and long-term persistence in care. Substance abuse treatment appears to facilitate engagement in HIV care, and access to evidence-based treatment for substance abuse is central to addressing the HIV epidemic. Strategies that show promise for HIV-infected substance abusers include integrated treatment models, directly observed therapy, and incentive-based interventions.
机译:物质滥用和成瘾在艾滋病毒感染者中非常普遍。药物滥用是一种重要的合并症,会影响HIV医疗管理的提供和结果。在本文中,我将回顾检查滥用药物和HIV治疗之间的关联以及改善该人群结局的潜在策略的数据,这些数据值得进一步研究。当前(而非过去)的药物滥用会对护理工作,接受抗逆转录病毒疗法,坚持治疗以及长期护理产生不利影响。药物滥用治疗似乎有助于参与艾滋病毒的护理,获得针对药物滥用的循证治疗对于解决艾滋病毒流行至关重要。对艾滋病毒感染者显示出希望的策略包括综合治疗模型,直接观察到的治疗以及基于激励的干预措施。

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