Expression of nuclear retinoic acid receptor in peripheral blood mononuclear cells (PBMC) of healthy subjects.

Szabova L; Macejova D; Dvorcakova M; Mostbock S; Blazickova S; Zorad S; Walrand S; Cardinault N; Vasson MP; Rock E; Brtko J

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Expression of nuclear retinoic acid receptor in peripheral blood mononuclear cells (PBMC) of healthy subjects.

机译：核视黄酸受体在健康受试者外周血单个核细胞（PBMC）中的表达。

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In vertebrates, both nuclear all-trans and 9-cis retinoic acid receptors (RAR and RXR) belonging to the steroid/thyroid/retinoid nuclear receptor superfamily play a crucial role in the vitamin A action. Qualitative analysis of all known RAR or RXR subtypes in both pooled and non-pooled peripheral blood mononuclear cells (PBMC) from healthy human subjects has been performed by reverse transcription and polymerase chain reaction (RT-PCR). Our data, based on qualitative RT-PCR analysis has shown that human PBMC are capable to express RAR alpha, RAR gamma, RXR alpha, and RXR beta.

机译：在脊椎动物中，属于类固醇/甲状腺/类视黄醇核受体超家族的核全反式和9-顺式视黄酸受体（RAR和RXR）在维生素A作用中起关键作用。已通过逆转录和聚合酶链反应（RT-PCR）对来自健康人类受试者的汇集和非汇集的外周血单核细胞（PBMC）中所有已知的RAR或RXR亚型进行了定性分析。我们基于定性RT-PCR分析的数据表明，人PBMC能够表达RAR alpha，RAR gamma，RXR alpha和RXR beta。

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《Life sciences》 |2003年第7期|共6页
作者
Szabova L; Macejova D; Dvorcakova M; Mostbock S; Blazickova S; Zorad S; Walrand S; Cardinault N; Vasson MP; Rock E; Brtko J;
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正文语种 eng
中图分类生命的起源;生命科学总论;
关键词
Cell Nucleus; Leukocytes; Mononuclear; Receptors; Retinoic Acid; DNA Primers; 细胞核; 白细胞; 单核; 受体; 维甲酸;

机译：Cell Nucleus;Leukocytes;Mononuclear;Receptors;Retinoic Acid;DNA Primers;细胞核;白细胞;单核;受体;维甲酸;

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1. Expression of nuclear retinoic acid receptor in peripheral blood mononuclear cells (PBMC) of healthy subjects. [J] . Szabova L, Macejova D, Dvorcakova M, Life sciences . 2003,第7期

机译：核视黄酸受体在健康受试者外周血单个核细胞（PBMC）中的表达。
2. Age-related change in the retinoid X receptor beta gene expression in peripheral blood mononuclear cells of healthy volunteers: Effect of 13-cis retinoic acid supplementation. [J] . Brtko J, Rock E, Nezbedova P, Mechanisms of Ageing and Development . 2007,第11a12期

机译：健康志愿者外周血单个核细胞中类维生素A X受体β基因表达的年龄相关变化：补充13-顺式视黄酸的作用。
3. Fasting induces changes in peripheral blood mononuclear cell gene expression profiles related to increases in fatty acid beta-oxidation: functional role of peroxisome proliferator activated receptor alpha in human peripheral blood mononuclear cells. [J] . Bouwens M, Afman LA, Muller M The American Journal of Clinical Nutrition: Official Journal of the American Society for Clinical Nutrition . 2007,第5期

机译：空腹诱导外周血单核细胞基因表达谱的变化，与脂肪酸β-氧化的增加有关：过氧化物酶体增殖物激活受体α在人外周血单核细胞中的功能作用。
4. Isolation and Characterization of Interferon-Induced Feline Tetherin (Bst-2) Protein Expressed by Peripheral Blood Mononuclear Cells (PBMCs) [C] . Dyah A. O. A. Pratama, Dyah Kinasih Wuragil, Nia Kurniawan International Conference on Bioinformatics and Nanomedicine from Natural Resources for Biomedical Research . 2019

机译：外周血单核细胞（PBMCs）表达干扰素诱导的猫蛋白（BST-2）蛋白的分离与表征
5. Effects of Environmental Endotoxins and Microgravity on Normal Human Peripheral Blood Mononuclear Cells (PBMCS) (Lymphocytes): Role of ETAS as an Immunomodulation Therapy [D] . Chaganti, Maitreyi. 2019

机译：环境内毒素和微重力对正常人外周血单个核细胞（PBMCS）（淋巴细胞）的影响：ETAS作为免疫调节治疗的作用
6. Expression of the activation antigen CD69 predicts functionality of in vitro expanded peripheral blood mononuclear cells (PBMC) from healthy donors and HIV-infected patients [O] . S D Nielsen, P Afzelius, A K ErsbØll, 1998

机译：激活抗原CD69的表达预测了来自健康供体和HIV感染患者的体外扩增外周血单个核细胞（PBMC）的功能
7. Aging affects the retinoic acid and the triiodothyronine nuclear receptor mRNA expression in human peripheral blood mononuclear cells [O] . C Feart, V Pallet, C Boucheron, 2005

机译：老化会影响人外周血单核细胞中的视黄酸和三碘甲醇核受体mRNA表达

Expression of nuclear retinoic acid receptor in peripheral blood mononuclear cells (PBMC) of healthy subjects.

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