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首页> 外文期刊>Life sciences >Bone-specific alkaline phosphatase activities in plasma and callus during callotasis in rabbits.
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Bone-specific alkaline phosphatase activities in plasma and callus during callotasis in rabbits.

机译：兔call症期间血浆和愈伤组织中的骨特异性碱性磷酸酶活性。

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Using the rabbit as an animal model, the changes of enzymatic activities of bone-specific alkaline phosphatase (ALP) in plasma and in the callus during callotasis were studied. Bone-specific ALP activities were measured by the wheatgerm agglutinin precipitation method. Distractions were performed on different groups of animals commencing on 3rd, 5th and 7th day after osteotomy. Bone-specific ALP activities in the plasma of all these groups dropped significantly on first few days compared with those values before osteotomy. However, when distraction was started, the plasma bone-specific ALP rose progressively until day 35 and resumed normal gradually until day 70. Immediate rises in enzymatic activities after distractions were observed in the 5th- and 7th-day treating groups but not in the 3rd-day treating group. The bone-specific ALP activities in the callus samples also increased until day 35 and gradually decreased. With the plasma bone-specific ALP as an indicator of the biological activities of theosteoblasts, the effect of external mechanical stimulation in a form of the tension stress on the biological tissue is well demonstrated in this study.
机译：以家兔为动物模型，研究了愈伤组织中血浆和愈伤组织中骨特异性碱性磷酸酶（ALP）酶活性的变化。通过小麦胚芽凝集素沉淀法测量骨特异性ALP活性。在截骨后第3、5和7天开始对不同组的动物进行分散注意力。与截骨术前的那些值相比，所有这些组的血浆中的骨特异性ALP活性在开始的几天中均显着下降。但是，开始分心时，血浆骨特异性ALP逐渐升高直至第35天，并逐渐恢复正常，直到第70天。分心后第5天和第7天治疗组的酶活性立即升高，而第3天则没有日治疗组。愈伤组织样品中的骨特异性ALP活性也增加直至第35天，然后逐渐下降。使用血浆骨特异性ALP作为成骨细胞生物学活性的指标，在​​这项研究中很好地证明了外部机械刺激以张应力的形式对生物组织的影响。

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