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Central nervous system fatigue alters autonomic nerve activity.

机译:中枢神经系统疲劳会改变自主神经的活动。

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AIMS: Fatigue is a common symptom in modern society. In order to clarify the mechanisms underlying fatigue, we examined the association between central nervous system fatigue and autonomic nerve activity. MAIN METHODS: The study group consisted of 20 healthy subjects. They performed the 2-back test for 30 min to induce fatigue. Just before and after the fatigue-inducing session, they completed the advanced trail making test (ATMT) for 30 min as a fatigue-evaluating task session. In order to measure autonomic nerve activity, electrocardiograms were monitored continuously throughout the experiment. KEY FINDINGS: After the fatigue-inducing task session, impaired task performance was demonstrated based on the total trial number and error counts of the ATMT. During the task session, although task performance as measured using the accuracy and the mean reaction time of the 2-back test was almost unchanged, electrocardiographic R-R wave interval analyses showed a decreased high-frequency component power and an increasing trend in the low-frequency component power/high-frequency component power ratio. SIGNIFICANCE: Decreased vagal nerve activity and increased sympathetic nerve activity are associated with central nervous system fatigue.
机译:目的:疲劳是现代社会的常见症状。为了阐明疲劳的潜在机制,我们研究了中枢神经系统疲劳与自主神经活动之间的关联。主要方法:研究组由20名健康受试者组成。他们进行了2次背部测试30分钟,以引起疲劳。在疲劳诱导课程之前和之后,他们完成了30分钟的高级跟踪测试(ATMT),作为疲劳评估任务课程。为了测量自主神经活动,在整个实验过程中连续监测心电图。主要发现:在引起疲劳的任务会话之后,基于ATMT的总试验次数和错误计数证明了任务性能受损。在任务过程中,尽管使用2-back测试的准确性和平均反应时间测量的任务执行情况几乎没有变化,但心电图RR波间隔分析显示高频分量功率降低,低频分量增加趋势分量功率/高频分量功率比。意义:迷走神经活动减少和交感神经活动增加与中枢神经系统疲劳有关。

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