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首页> 外文期刊>Life sciences >VISUALIZATION OF GENE EXPRESSION OF PROLACTIN RECEPTORS (PRL-R) BY IN SITU HYBRIDIZATION, IN TYPHLONECTES COMPRESSICAUDUS, A GYMNOPHIONAN AMPHIBIAN
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VISUALIZATION OF GENE EXPRESSION OF PROLACTIN RECEPTORS (PRL-R) BY IN SITU HYBRIDIZATION, IN TYPHLONECTES COMPRESSICAUDUS, A GYMNOPHIONAN AMPHIBIAN

机译：原产地杂交，在雄性两栖动物两栖型无性系中催乳素受体（PRL-R）基因表达的可视化

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摘要

The expression of the short and long forms of prolactin receptors (PRL-R) mRNA was studied in various types of tissues from Typhlonectes compressicaudus, an amphibian, by quantitative in situ hybridization. Both forms were expressed in all the types of tissues studied. In the liver, small intestine and hypophysis, the mRNA coding for the short form of PRL-R was more strongly expressed than the mRNA coding for the long form and vice-versa for the stomach, spleen and kidneys. In the female liver, quantification showed a higher value of mRNA expression mid-way through pregnancy than during the sexual inactivity period. This result was found to be correlated with the reserve function of the liver. In the kidney and small intestine, the presence of PRL-R was correlated with the hydromineral function. A comparison with certain mammals was also established. These results confirm the ubiquity of PRL effects on metabolic regulation, and suggest a phylogenic conservation of its receptors. [References: 47]
机译：通过定量原位杂交，研究了两栖类Typholonectes compressicaudus（两栖动物）的各种类型组织中催乳素受体（PRL-R）mRNA的短和长形式的表达。两种形式均在所研究的所有类型的组织中表达。在肝脏，小肠和垂体中，编码PRL-R短形式的mRNA比编码长形式的mRNA更强，反之亦然，对胃，脾脏和肾脏反之亦然。在女性肝脏中，定量分析显示，在怀孕中期，mRNA表达的值高于无性活动期间。发现该结果与肝脏的储备功能相关。在肾脏和小肠中，PRL-R的存在与矿物质功能有关。还确定了与某些哺乳动物的比较。这些结果证实了PRL对代谢调节的普遍作用，并暗示了其受体的系统发育保守性。 [参考：47]

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