Serotonin and vasoconstrictor synergism [Review]

Yildiz O.; Purdy RE.; Smith JR.

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Serotonin and vasoconstrictor synergism [Review]

机译：5-羟色胺与血管收缩剂的协同作用[综述]

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Contractile synergism between serotonin (5-hydroxytryptamine, 5-HT) and other vasoconstrictor substances has been observed in a number of peripheral and cerebrovascular blood vessels. This phenomenon may play an important role in certain pathological states such as hypertension, peripheral vascular disease, and coronary spasm. In the present review, we summarize studies on the synergism between serotonin and other vasoconstrictor agents and focus on a recently described type of vasoconstrictor synergism in which precontraction with a non-5-HT receptor agonist yields an enhanced contractile response to serotonin which is mediated by previously inactive or "silent" 5-HT receptor subtypes. [References: 81]

机译：在许多外周和脑血管中都观察到了5-羟色胺（5-羟色胺，5-HT）与其他血管收缩物质之间的收缩协同作用。这种现象在某些病理状态如高血压，周围血管疾病和冠状动脉痉挛中可能起重要作用。在本综述中，我们总结了关于5-羟色胺与其他血管收缩剂之间协同作用的研究，并集中于最近描述的血管收缩剂协同作用类型，其中与非5-HT受体激动剂的预收缩产生对5-羟色胺的收缩反应，该收缩反应是由5-羟色胺介导的先前无活性或“沉默”的5-HT受体亚型。 [参考：81]

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《Life sciences》 |1998年第19期|共10页
作者
Yildiz O.; Purdy RE.; Smith JR.;
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正文语种 eng
中图分类生命的起源;生命科学总论;
关键词
Serotonin; Contraction; Synergism; Mediate 5-hydroxytryptamine-induced contraction; Isolated iliac artery; Isolated mesenteric-artery; Smooth-muscle contraction; Internal mammary artery; Isolated femoral-artery; Isolated saphenous-vein; Human coronary-arteries; Isolated ear artery; 5-ht1-like receptor;

机译：5羟色胺;收缩;协同作用;介导5-羟色胺诱导的收缩;动脉分离;肠系膜动脉分离;平滑肌收缩;乳内动脉分离;股骨动脉;隐隐静脉分离;人冠状动脉;耳廓;5-ht1样受体;

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1. Serotonin and vasoconstrictor synergism [Review] [J] . Yildiz O., Purdy RE., Smith JR. Life sciences . 1998,第19期

机译：5-羟色胺与血管收缩剂的协同作用[综述]
2. Plasma Membrane Depolarization and Activation of Receptors for Endogenous Vasoconstrictors as Possible Mechanisms of Potentiation of Vasoconstrictive Response to Serotonin in Traumatic Shock in Rats [J] . L. M. Kozhevnikova, A. G. Davydova, P. V. Avdonin Biology Bulletin . 2009,第3期

机译：血浆膜去极化和内源性血管收缩受体激活可能是大鼠创伤性休克中血清素对血管收缩反应增强的可能机制
3. Vasoconstrictor Effect of Endothelin in Isolated Perfused Stomach of the Rat in Comparison with Noradrenaline and Serotonin [J] . Kazuo WATANABE, Kenji YOGO, Shingo YANO Japanese Journal of Pharmacology . 1990,第1期

机译：与去甲肾上腺素和血清素比较，内皮素在大鼠离体灌流胃中的血管收缩作用
4. SEROTONIN RECEPTOR AND SEROTONIN REUPTAKE TRANSPORTER EXPRESSION IN PRIMARY AND METASTATIC CANINE OSTEOSARCOMA CELL LINES. [C] . Shay Bracha, Kenine E Comstock, Evan T Keller, Annual conference of the Veterinary Cancer Society . 2008

机译：血清素受体和血清素再摄取转运蛋白表达在原发性和转移性犬骨瘤细胞系中。
5. STATUS-QUALITY SYNERGISMS IN THE PEER REVIEW OF MANUSCRIPTS [D] . FESTA, ROGER REGINALD 1982

机译：手稿同行评审中的状态质量协同
6. Systems Biology and Polygenic Traits: Elevated K+ channel activity opposes vasoconstrictor response to serotonin in cerebral arteries of the Fawn Hooded Hypertensive rat [O] . Mallikarjuna R. Pabbidi, Richard J. Roman -1

机译：系统生物学和多基因性状：K +通道活性升高与小鹿派生的高血压大鼠脑动脉中对5-羟色胺的血管收缩反应相反。
7. Elevated K+ channel activity opposes vasoconstrictor response to serotonin in cerebral arteries of the Fawn Hooded Hypertensive rat [O] . Mallikarjuna R. Pabbidi, Richard J. Roman 2017

机译：K +频道活性升高反对血管收缩剂对血清蒙皮高血压大鼠脑动脉中的血清素的反应
8. Review of synergisms in materials erosion due to multispecies impact. [R] . Haasz, A. A., Auciello, O., Stangeby, P. C. 1985

机译：审查由于多种类影响造成的材料侵蚀的协同作用。

Serotonin and vasoconstrictor synergism [Review]

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