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Effects of inhaled corticosteroids on voice production in healthy adults

机译：吸入皮质类固醇对健康成年人语音产生的影响

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The isolated effects of inhaled corticosteroids (ICS) on voice production were examined in 30 healthy adults with no known pre-existing airway disease. All participants followed a daily ICS treatment regime of 500 mu g in the morning and evening over a 6-day period. Sustained vowels and connected speech samples were audio recorded before, during, and after the ICS regime. Each participant's audio recorded samples were acoustically analysed. Results revealed that ICS has a short-term detrimental effect on various acoustic properties of voice. These effects were more evident in connected speech compared to isolated vowel productions. All acoustic parameters returned to normalcy after discontinuing the ICS. The study provides insight as to the influence of ICS on healthy voice production.
机译：在30名没有已知气道疾病的健康成年人中，检查了吸入皮质类固醇（ICS）对声音产生的孤立影响。所有参与者在6天的时间内每天早晨和晚上都遵循500克的ICS每日治疗方案。在ICS体制之前，之中和之后都记录了持续的元音和连接的语音样本。对每个参与者的音频记录样本进行声学分析。结果表明，ICS对语音的各种声学特性具有短期有害影响。与孤立的元音产品相比，这些效果在关联语音中更为明显。中断ICS后，所有声学参数均恢复正常。该研究提供了有关ICS对健康语音产生的影响的见解。

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