Liver proliferation: The GUCD1/NEDD4-1 connection

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Liver proliferation: The GUCD1/NEDD4-1 connection

机译：肝增殖：GUCD1 / NEDD4-1连接

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In order to preserve its role(s) in the control of metabolism and detoxification, the liver possesses the unique ability to fully recover its original mass and function after injury.12 Following surgical removal or cell loss caused by toxic or viral damage, quiescent hepatocytes trigger a proliferative process, so that the initial liver mass is restored.12 Such a complex process, known as liver regeneration (although "compensatory hyperplasia" would describe this phenomenon more accurately) involves a plethora of finely orchestrated cellular and molecular events that are only partly known.

机译：为了保留其在代谢和排毒控制中的作用，肝脏具有独特的能力，可以在损伤后完全恢复其原始质量和功能。12由于毒性或病毒损伤导致的手术切除或细胞丢失后，静止的肝细胞触发增殖过程，从而恢复初始肝脏质量。12这种被称为肝脏再生的复杂过程（尽管“代偿性增生”将更准确地描述这一现象）涉及许多精心策划的细胞和分子事件部分已知。

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《Cell cycle》 |2014年第13期|共2页
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CalvisiD.F.;
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正文语种 eng
中图分类细胞生物学;
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1. Liver proliferation: The GUCD1/NEDD4-1 connection [J] . CalvisiD.F. Cell cycle . 2014,第13期

机译：肝增殖：GUCD1 / NEDD4-1连接
2. NEDD4 controls the expression of GUCD1, a protein upregulated in proliferating liver cells [J] . BelletM.M., PiobbicoD., BartoliD., Cell cycle . 2014,第12期

机译：NEDD4控制GUCD1的表达，GUCD1是在增殖的肝细胞中上调的蛋白
3. Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells [J] . Quirit Jeanne G., Lavrenov Sergey N., Poindexter Kevin, Biochemical Pharmacology . 2017,第期

机译：吲哚-3-甲醇（I3C）类似物是NEDD4-1泛素连接酶活性的有效的小分子抑制剂，其破坏人黑素瘤细胞的增殖
4. The Effect of Culture Conditions on Liver Function and Proliferation of Hepatic Cells for Bio-Artificial Liver [C] . Yumi Narita, Kozue Kaito, Takeshi Omasa, Annual Meeting of the Japanese Association for Animal Cell Technology . 2009

机译：培养条件对生物人工肝脏肝功能和肝细胞增殖的影响
5. Selective translocation of cell-impermeable toxins into cancer cells: pHLIP mediated delivery of phallotoxins inhibits cancer proliferation. [D] . Wijesinghe, Dayanjali Diluka. 2011

机译：细胞不可渗透毒素选择性转移到癌细胞中：pHLIP介导的鬼笔毒素传递抑制了癌症的扩散。
6. Exosomal Circ-ZNF652 Promotes Cell Proliferation Migration Invasion and Glycolysis in Hepatocellular Carcinoma via miR-29a-3p/GUCD1 Axis [O] . Yuhui Li, Hongliang Zang, Xue Zhang, 2020

机译：外泌体循环ZNF652通过MIR-29A-3P / GUCD1轴促进肝细胞癌中的细胞增殖迁移侵袭和糖酵解促进肝细胞癌
7. Liver proliferation: The GUCD1/NEDD4–1 connection [O] . Diego Calvisi 2014

机译：肝增殖：GUCD1 / NEDD4-1连接

Liver proliferation: The GUCD1/NEDD4-1 connection

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