APC activators caught by their tails?

Vodermaier HC; Peters JM

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APC activators caught by their tails?

机译：APC激活剂被它们的尾巴抓住了吗？

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The complexity of the Anaphase-Promoting Complex (APC), the major ubiquitin ligase in mitotic control, has been puzzling investigators ever since its discovery. Recent biochemical and genetic studies have now provided insights not only into the architecture of the complex, but also into how activators are recruited to the APC. In this article, we discuss the implications of these findings on our current understanding of APC activation.

机译：自从其被发现以来，促进有丝分裂的主要泛素连接酶“后期促进复合物”（APC）的复杂性就一直困扰着研究人员。现在，最近的生化和遗传研究不仅提供了对复合物结构的了解，而且还提供了如何将激活剂招募到APC的见解。在本文中，我们讨论了这些发现对我们当前对APC激活的理解的含义。

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《Cell cycle》 |2004年第3期|共2页
作者
Vodermaier HC; Peters JM;
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正文语种 eng
中图分类细胞生物学;
关键词
APC Gene; Complex; Recent; Genetic; control;

机译：APC基因;复杂;最近;遗传;对照;

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专利

1. APC activators caught by their tails? [J] . Vodermaier HC, Peters JM Cell cycle . 2004,第3期

机译：APC激活剂被它们的尾巴抓住了吗？
2. Activated prothrombin complex concentrate (APCC)-mediated activation of factor (F)VIII in mixtures of FVIII and APCC enhances hemostatic effectiveness [J] . YadaK., NogamiK., OgiwaraK., Journal of thrombosis and haemostasis: JTH . 2013,第5期

机译：活化的凝血酶原复合物浓缩物（APCC）介导的FVIII和APCC混合物中因子（F）VIII的活化增强了止血效果
3. LncAPC LncAPC drives Wnt/β‐catenin activation and liver TIC self‐renewal through EZH2 mediated APC transcriptional inhibition [J] . Fu Xiaomin, Lin Jizhen, Qin Fujun, Molecular Carcinogenesis . 2018,第3期

机译：LNCAPC LNCAPC通过EzH2介导的APC转录抑制驱动WNT /β-Catenin活化和肝脏TIC自我更新
4. Preliminary Performance Analysis of the LAPCAT-MR2 by means of Nose-to-Tail Computations [C] . T. Langener, J. Steelant, P. Roncioni, AIAA/3AF international space planes and hypersonic systems and technologies conference . 2012

机译：通过鼻对尾计算对LAPCAT-MR2进行初步性能分析
5. Polyanions Provide Selective Control of APC/C Interactions with the Activator Subunit [D] . Mizrak, Arda. 2020

机译：Polyanions提供与激活亚单元的APC / C相互作用的选择性控制
6. Detection and molecular characterization of Cryptosporidium species in wild-caught pet spiny-tailed lizards [O] . Rie Kubota, Toshihiro Tokiwa, Katsuki Matsubara, 2020

机译：野外捕获的宠物多刺尾蜥的隐孢子虫种类的检测和分子表征
7. APC Activators Caught by Their Tails? [O] . Hartmut C. Vodermaier, Jan-Michael Peters 2004

机译：APC激活者被尾巴抓住了吗？

APC activators caught by their tails?

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