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Excretion of purine base derivatives after intake of bacterial protein meal in pigs.

机译：猪摄入细菌蛋白粉后嘌呤碱基衍生物的排泄。

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摘要

Bacterial protein meal has a high content of protein but also of RNA and DNA. Sixteen barrows were allocated to four diets containing increasing levels of bacterial protein meal (BPM), from weaning to 80 kg live weight, to evaluate whether the RNA and DNA contents of BPM influenced the retention of nitrogen. It was hypothesised that an increased intake of RNA and DNA would lead to an increased urinary excretion of purine base derivatives and increased plasma concentrations. Retention of nitrogen was unaffected by dietary content of BPM (P=0.08) and the urinary excretion of purine base derivatives increased with increasing dietary content of BPM. No differences in fasting plasma concentration of uric acid, xanthine and hypoxanthine were observed. It can therefore be concluded that increasing levels of dietary BPM maintained protein accretion and led to changes in excretion of purine derivatives, but did not cause uricogenic effects in the pigs..
机译：细菌蛋白粉不仅蛋白质含量高，而且RNA和DNA含量也很高。从断奶仔猪体重增加到80公斤活重，将十六只公猪分配到四种日粮中含量不断增加的细菌蛋白粉（BPM），以评估BPM的RNA和DNA含量是否影响氮的保留。假设RNA和DNA的摄入增加将导致嘌呤碱衍生物的尿排泄增加和血浆浓度增加。饮食中BPM的含量对氮的保留没有影响（P = 0.08），并且随着饮食中BPM含量的增加，嘌呤碱衍生物的尿排泄量增加。空腹血浆尿酸，黄嘌呤和次黄嘌呤浓度无差异。因此可以得出结论，日粮中BPM水平的增加可维持蛋白质的积聚，并导致嘌呤衍生物的排泄发生变化，但不会对猪造成尿毒症作用。

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