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首页> 外文期刊>Radiology >Noninvasive coronary angiography with 64-section CT: effect of average heart rate and heart rate variability on image quality.
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Noninvasive coronary angiography with 64-section CT: effect of average heart rate and heart rate variability on image quality.

机译：64层CT的无创冠状动脉造影：平均心率和心率变异性对图像质量的影响。

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PURPOSE: To evaluate prospectively the effect of average heart rate and heart rate variability on image quality at 64-section computed tomographic (CT) coronary angiography. MATERIALS AND METHODS: The study protocol had local ethics committee approval; written informed consent was obtained. There were 125 patients (45 women, 80 men; mean age, 59.9 years +/- 12.9 [standard deviation]; 79 receiving beta-blockers) who underwent 64-section CT coronary angiography with retrospective electrocardiographic gating. Data sets were reconstructed in 5% steps from 20% to 80% of R-R interval. Heart rate variability was calculated as 1 standard deviation from mean rate during scanning. Two observers rated image quality of each coronary segment at least 1.5-mm diameter (1 = no motion artifacts, 5 = not evaluative). Repeated analysis of variance measurements were performed to evaluate quantitative parameters. Pearson correlation analysis was performed to compare image quality in each patient with average heart rate andheart rate variability. RESULTS: Average heart rate was 63.3 beats per minute +/- 13.1, with variability of 3.2 beats per minute +/- 2.1. Diagnostic image quality (score < or = 3) was attained in 1821 of 1836 segments at the best reconstruction interval. There was no correlation between mean heart rate and image quality for all segments of the right coronary and left anterior descending arteries, but there was a significant correlation for left circumflex artery (r = 0.33, P < .05). Heart rate variability was correlated with image quality overall (r = 0.75, P < .001) and for each coronary artery. Heart rate was less variable and image quality was better (P < .05) in patients receiving beta-blockers. Best image quality was obtained in diastole with heart rate less than 80 beats per minute and in systole with faster heart rate. CONCLUSION: Coronary angiography with 64-section CT provides diagnostic image quality within a wide range of heart rates. Reducing average heart rate and heart rate variability is beneficial for reducing artifacts.
机译：目的：前瞻性评估平均心率和心率变异性对64层计算机断层扫描（CT）冠状动脉造影的图像质量的影响。材料与方法：研究方案已获得当地伦理委员会的批准。已获得书面知情同意。共有125例患者（平均年龄59.9岁+/- 12.9 [标准差]; 79例接受β受体阻滞剂）行回顾性心电门控的64层CT冠状动脉造影。从R-R间隔的20％到80％以5％的步长重建数据集。心率变异性计算为扫描过程中平均速率的1个标准差。两名观察者对每个冠状动脉节段的图像质量进行了评估，评估的直径至少为1.5毫米（1 =无运动伪影，5 =无法评估）。进行方差测量的重复分析以评估定量参数。进行了Pearson相关分析，以比较每位患者的图像质量与平均心率和心率变异性。结果：平均心律为每分钟63.3拍+/- 13.1，变异为每分钟3.2拍+/- 2.1。在1821个1836个分段中，以最佳重建间隔获得了诊断图像质量（得分<或= 3）。右冠状动脉和左前降支各段的平均心率与图像质量之间无相关性，但左旋支动脉有显着相关性（r = 0.33，P <.05）。心率变异性与总体图像质量（r = 0.75，P <.001）以及每个冠状动脉的图像质量相关。接受β受体阻滞剂治疗的患者的心率变化较小，图像质量更好（P <.05）。舒张期心率每分钟小于80次，收缩期心率更快，可获得最佳图像质量。结论：64层螺旋CT冠状动脉造影可在广泛的心率范围内提供诊断图像质量。降低平均心率和心率变异性有助于减少伪影。

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