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首页> 外文期刊>Radiology >Biventricular systolic function and mass studied with MR imaging in children with pulmonary regurgitation after repair for tetralogy of Fallot.
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Biventricular systolic function and mass studied with MR imaging in children with pulmonary regurgitation after repair for tetralogy of Fallot.

机译：法洛四联症修复后肺关闭不全患儿的双室收缩功能和质量研究（MR成像）。

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摘要

PURPOSE: To study biventricular systolic function and mass of the heart in young patients with residual pulmonary regurgitation who had undergone surgical correction of tetralogy of Fallot. MATERIALS AND METHODS: Transverse gradient-echo magnetic resonance (MR) images covering both ventricles were obtained in 19 patients who had undergone corrective surgery for tetralogy of Fallot at the age of 1.5 years +/- 1 and in 12 age-matched control subjects. In addition, MR velocity maps of the pulmonary artery were obtained. Biventricular volumes, ejection fraction and myocardial mass, and pulmonary flow volumes were measured. Exercise tests were performed in 17 patients. RESULTS: The right ventricular ejection fraction was lower (P < .001) and the right ventricular mass was higher (P < .0005) in patients than in control subjects; the left ventricular ejection fraction was lower (P < .0005) in patients and correlated statistically significantly with pulmonary regurgitation (r = -.68; P < .005). Exercise performance inversely correlated with pulmonary regurgitation (tau = -0.5; P = .01). CONCLUSION: In children who undergo early surgical repair of tetralogy of Fallot, residual pulmonary regurgitation correlates with biventricular systolic dysfunction and diminished exercise capacity. Despite successful surgical correction, right ventricular hypertrophy may persist.
机译：目的：研究接受了法洛四联症手术矫正的年轻残留肺关闭不全患者的双室收缩功能和心脏质量。材料与方法：在19例接受法洛氏四联症矫正手术的19例年龄为1.5岁+/- 1的患者中以及12例年龄匹配的对照受试者中获得了覆盖两个心室的横向梯度回波磁共振（MR）图像。另外，获得了肺动脉的MR速度图。测量双心室容积，射血分数和心肌质量以及肺血流量。对17名患者进行了运动测试。结果：与对照组相比，患者的右心室射血分数较低（P <.001），右心室质量较高（P <.0005）。患者的左心室射血分数较低（P <.0005），并且与肺返流在统计学上显着相关（r = -.68; P <.005）。运动表现与肺返流呈负相关（tau = -0.5; P = 0.01）。结论：在接受早期法洛四联症手术修复的儿童中，残留的肺返流与双心室收缩功能障碍和运动能力下降有关。尽管手术矫正成功，但右心室肥厚仍可能持续。

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