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首页> 外文期刊>Radiology >Fulminant hepatic failure: observation with serial CT.
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Fulminant hepatic failure: observation with serial CT.

机译：重型肝衰竭：连续CT观察。

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PURPOSE: To determine the imaging characteristics of fulminant hepatic failure at serial computed tomography (CT) and to assess if any CT findings have prognostic value. MATERIALS AND METHODS: In 40 patients, 207 CT scans were analyzed retrospectively. Thirty-four patients had fulminant hepatic failure (acute in seven and subacute in 27), and six had late-onset hepatic failure. Twenty-one patients died of hepatic failure. CT was performed soon after the onset of coma and repeated weekly. Liver volume was measured by tracing the hepatic contour and summing the areas to estimate whole-liver volume. RESULTS: Liver volumes in survivors (n = 19) and nonsurvivors (n = 21), respectively, were 1,090 cm3 +/- 300 and 830 cm3 +/- 240 at initial CT and 1,130 cm3 +/- 310 and 700 cm3 +/- 280 at last CT (P = .0001). III-defined hypoattenuating areas were noted in 20 patients and were distributed in a solitary (n = 13), multiple (n = 6), or diffuse (n = 1) pattern. At follow-up CT, the area of hypoattenuation increased in six patients (five nonsurvivors) and disappeared or markedly decreased in four survivors. An increase in or late occurrence of ascites was noted in 15 patients (14 nonsurvivors, P = .0001). CONCLUSION: Liver volumes at the initial and last CT examinations and an increase in or late occurrence of ascites are useful prognostic findings.
机译：目的：确定连续计算机断层扫描（CT）暴发性肝衰竭的影像学特征，并评估是否有任何CT表现具有预后价值。材料与方法：回顾性分析40例患者的207例CT扫描。 34例发生暴发性肝衰竭（7例急性发作，27例亚急性），晚期肝衰竭6例。 21名患者死于肝功能衰竭。昏迷发作后立即进行CT检查，并每周重复一次。通过追踪肝轮廓并求和面积以估计全肝体积来测量肝脏体积。结果：在初始CT时，幸存者（n = 19）和非幸存者（n = 21）的肝体积分别为1,090 cm3 +/- 300和830 cm3 +/- 240，以及1,130 cm3 +/- 310和700 cm3 + / -最后一次CT时为280（P = .0001）。 III定义的低衰减区域在20例患者中发现，并以单独（n = 13），多个（n = 6）或弥散（n = 1）模式分布。在随访CT中，六名患者（五名非幸存者）的低衰减区域增加，四名幸存者消失或明显减少。 15例患者中腹水增加或较晚发生（14例非幸存者，P = .0001）。结论：最初和最后一次CT检查的肝脏体积以及腹水的增加或晚期发生是有益的预后发现。

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