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首页> 外文期刊>Radiology >Use of liquid ventilation with perflubron during extracorporeal membrane oxygenation: chest radiographic appearances.
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Use of liquid ventilation with perflubron during extracorporeal membrane oxygenation: chest radiographic appearances.

机译：在体外膜氧合期间使用全通气进行液体通气：胸部X线影像表现。

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PURPOSE: To assess the effectiveness of performing liquid ventilation with perflubron in neonates with severe respiratory failure or pulmonary hypertension who receive extracorporeal membrane oxygenation (ECMO) life support. MATERIALS AND METHODS: We studied an infant (aged 1 month) and a neonate with respiratory failure who underwent ECMO and liquid ventilation with perflubron, which was slowly instilled via an endotracheal tube (in the infant, 40 mL for more than 1 hour; in the neonate, 28 mL within 1 hour). RESULTS: The infant survived termination of ECMO support and has been breathing room air since 6 months of age. The neonate died soon after ECMO support was withdrawn. CONCLUSION: A minority of neonates or infants with severe respiratory failure or pulmonary hypertension do not respond adequately to treatment with ECMO and are almost certain to die with termination of ECMO support. Liquid ventilation with perflubron offers a potential salvage therapy in this patient population. In addition, perflubron is a good contrast agent to use in the evaluation of neonatal pulmonary abnormalities.
机译：目的：评估在患有严重呼吸衰竭或肺动脉高压并接受体外膜氧合作用（ECMO）生命支持的新生儿中，进行全氟龙液体通气的有效性。材料与方法：我们研究了一名婴儿（1个月大）和一名患有呼吸衰竭的新生儿，他们接受了ECMO和全氟溴的液体通气，并通过气管导管缓慢滴注（婴儿中，40 mL注射1小时以上;新生儿，一小时内注射28毫升）。结果：该婴儿在ECMO支持终止后幸存下来，并且自6个月大以来一直在呼吸室内空气。 ECMO撤回支持后不久，新生儿死亡。结论：少数患有严重呼吸衰竭或肺动脉高压的新生儿或婴儿对ECMO的治疗没有足够的反应，并且几乎可以肯定的是，终止ECMO支持会死亡。全氟溴酸钠的液体通气在该患者人群中提供了潜在的挽救疗法。另外，全氟醚是用于评估新生儿肺部异常的良好造影剂。

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