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Pulmonary Langerhans cell histiocytosis: evolution of lesions on CT scans.

机译:肺朗格汉斯细胞组织细胞增生:CT扫描上病变的演变。

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PURPOSE: To document the evolution of pulmonary lesions of Langerhans cell histiocytosis (LCH) with sequential computed tomography (CT). MATERIALS AND METHODS: Initial and final CT scans of 21 patients with LCH and CT evidence of pulmonary disease were compared retrospectively. Histologic confirmation of pulmonary involvement was available in 11 patients. RESULTS: On initial CT images, a nodular pattern (n = 14) was seen more frequently than a cystic pattern (n = 7). On final CT images, a cystic pattern (n = 14) was seen more often than a nodular one (n = 6). There was complete resolution of parenchymal abnormality in one case. Nodular opacities, thick-walled cysts, and ground-glass opacities underwent regression. Thin-walled cysts, linear opacities, and emphysematous lesions remained unchanged or progressed. CONCLUSION: Pulmonary CT allows good assessment of the evolution of LCH lesions. Nodular lesions probably represent active disease and often undergo regression or transform into cysts.
机译:目的:用顺序计算机断层扫描(CT)记录朗格汉斯细胞组织细胞增生症(LCH)肺部病变的演变。材料与方法:回顾性比较21例LCH患者的初次和最终CT扫描以及肺部疾病的CT证据。肺部受累的组织学证实为11例患者。结果:在最初的CT图像上,结节型(n = 14)比囊性型(n = 7)更常见。在最终的CT图像上,囊肿型(n = 14)比结节型(n = 6)更常见。一例完全消除了实质性异常。结节性混浊,厚壁囊肿和毛玻璃样混浊均消退。薄壁囊肿,线性混浊和气肿性病变保持不变或进展。结论:肺部CT可以很好地评估LCH病变的发展。结节性病变可能代表活动性疾病,通常会消退或转化为囊肿。

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