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首页> 外文期刊>Radiology >Hepatic metastases: percutaneous radio-frequency ablation with cooled-tip electrodes.
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Hepatic metastases: percutaneous radio-frequency ablation with cooled-tip electrodes.

机译：肝转移：尖端冷电极经皮射频消融。

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摘要

PURPOSE: To assess the feasibility and safety of using cooled-tip electrodes to increase the volume of coagulation necrosis obtained or reduce the number of treatment sessions necessary with percutaneous tumor radio-frequency (RF) ablation. MATERIALS AND METHODS: Twenty-nine patients with 44 hepatic metastases (1.3-5.1 cm diameter) from colorectal (n = 22), gastric (n = 5), pancreatic (n = 1), or breast (n = 1) carcinoma were treated with RF ablation using cooled-tip, 18-gauge electrodes with 2-3 cm tip exposure. Each tumor was treated in one or two treatment sessions. RESULTS: Technical success, ablation of all visualized tumor, was achieved in 40 (91%) metastases. Findings at computed tomography (CT) and magnetic resonance (MR) imaging performed 3-6 months after treatment confirmed complete necrosis of the entire metastasis in 66%. Disease-free survival was 50% at 12 months and 33% at 18 months, with localized progression of disease in 34% of treated lesions. Overall survival was 100%, 94%, and 89% at 6, 12, and 18 months, respectively. Only one complication, self-limited hemorrhage, was seen. CONCLUSION: Use of cooled-tip electrodes was a safe and feasible adjunct for tumor RF ablation therapy that produced larger volumes of coagulation necrosis with fewer electrode insertions than is produced with other RF ablation techniques.
机译：目的：评估使用冷端电极以增加获得的凝血坏死量或减少经皮肿瘤射频（RF）消融术所需治疗次数的可行性和安全性。材料与方法：29例来自大肠癌（n = 22），胃癌（n = 5），胰腺癌（n = 1）或乳腺癌（n = 1）的44例肝转移（直径1.3-5.1 cm）。射频消融，使用尖端为2-3 cm的18针冷尖电极进行射频消融。在一个或两个疗程中治疗每种肿瘤。结果：40例（91％）转移瘤取得了技术成功，所有可视化肿瘤均被消融。治疗后3-6个月进行的计算机断层扫描（CT）和磁共振成像（MR）成像结果证实了66％的转移灶完全坏死。在12个月时无病生存率为50％，在18个月时为33％，在34％的已治疗病灶中局部疾病进展。在6、12和18个月时，总生存率分别为100％，94％和89％。仅观察到一种并发症，即自限性出血。结论：使用冷端电极是肿瘤射频消融治疗的一种安全可行的辅助手段，与其他射频消融技术相比，该技术产生的凝血坏死量更大，电极插入数量更少。

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