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首页> 外文期刊>Radiology >Discrete lung involvement in systemic lupus erythematosus: CT assessment.
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Discrete lung involvement in systemic lupus erythematosus: CT assessment.

机译：离散性肺累及系统性红斑狼疮：CT评估。

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PURPOSE: To study the computed tomographic (CT) appearance of early lung involvement in systemic lupus erythematosus (SLE). MATERIALS AND METHODS: In a prospective study, 48 patients with serologically confirmed SLE but no prior clinical evidence of lung involvement underwent chest radiography, CT, and lung function tests. Radiographs and CT scans were compared, and CT scans were evaluated for signs suggestive of parenchymal and pleural disease. Extent and distribution of disease were determined. CT findings were correlated with clinical and functional data. RESULTS: Of 45 patients with normal chest radiographs, 17 (38%) had abnormal CT findings. Extent of disease was statistically significantly correlated with duration of clinical history (r = .93) and decreased single-breath diffusing capacity for carbon monoxide (r = .8) and ratio of forced expiratory volume in 1 second to forced vital capacity (r = .77). CONCLUSION: CT is superior to chest radiography for detection of functionally relevant pulmonary disease and is an important adjunct in early assessment of SLE.
机译：目的：研究早期肺累及系统性红斑狼疮（SLE）的计算机断层扫描（CT）表现。材料与方法：在一项前瞻性研究中，对48例经血清学检查确诊为SLE但先前没有肺部受累临床证据的患者进行了胸部X射线照相，CT和肺功能检查。比较了射线照片和CT扫描，并评估了CT扫描是否有实质性和胸膜疾病的体征。确定疾病的程度和分布。 CT表现与临床和功能数据相关。结果：在45例胸片正常的患者中，有17例（38％）的CT表现异常。疾病程度与临床病史持续时间（r = .93）以及单呼吸一氧化碳扩散能力（r = .8）和1秒强迫呼气量与强迫肺活量的比率显着相关（r = .93） .77）。结论：在功能相关性肺部疾病的检测方面，CT优于胸部X线摄影，是SLE早期评估的重要辅助手段。

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