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Calcification of coronary arteries: detection and quantification with double-helix CT.

机译:冠状动脉钙化:双螺旋CT检测和定量。

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PURPOSE: To evaluate the accuracy of double-helix computed tomography (CT) in coronary artery calcification detection and quantification. MATERIALS AND METHODS: One hundred sixty patients with coronary disease (135 men, 25 women; age range, 45-62 years), of whom 138 had obstructive (stenosis of > 50% of diameter; n = 129) or mild (< 50% stenosis; n = 9) coronary artery disease (CAD) and 22 had normal coronary arteries (per angiographic findings), and 56 age-matched healthy control subjects underwent double-helix CT. RESULTS: Double-helix CT findings indicated that calcification was significantly more prevalent in patients with CAD (> 83%) than in patients with normal coronary arteries (27%) or in healthy control subjects (34%; P < .01). Sensitivity in detecting obstructive CAD was high (91%); however, specificity was low (52%) because of calcification in nonobstructive lesions. Comparison of double-helix CT and angiographic findings indicated that double-helix CT was 84% accurate with positive and negative predictive values of 89% and 59%, respectively. CONCLUSION: Double-helix CT is a useful noninvasive method for detection and quantification of coronary artery calcification.
机译:目的:评估双螺旋计算机断层扫描(CT)在冠状动脉钙化检测和定量中的准确性。材料与方法:一百六十例患有冠心病的患者(男性135例,女性25例;年龄范围45-62岁),其中138例患有阻塞性疾病(直径> 50%狭窄; n = 129)或轻度(<50)狭窄百分比; n = 9)冠状动脉疾病(CAD)和22例冠状动脉正常(根据血管造影结果),并且56位年龄匹配的健康对照受试者接受了双螺旋CT检查。结果:双螺旋CT结果表明,CAD患者(> 83%)的钙化明显高于正常冠状动脉患者(27%)或健康对照组的钙化(34%; P <.01)。检测阻塞性CAD的敏感性很高(91%);然而,由于非阻塞性病变的钙化,特异性较低(52%)。双螺旋CT和血管造影结果的比较表明,双螺旋CT的准确度为84%,阳性和阴性的预测值分别为89%和59%。结论:双螺旋CT是一种有用的非侵入性方法,用于检测和定量冠状动脉钙化。

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