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首页> 外文期刊>Renal failure. >Factors related to fatigue in Chinese patients with end-stage renal disease receiving maintenance hemodialysis: a multi-center cross-sectional study
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Factors related to fatigue in Chinese patients with end-stage renal disease receiving maintenance hemodialysis: a multi-center cross-sectional study

机译：接受维持性血液透析的中国终末期肾病患者与疲劳相关的因素：多中心横断面研究

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Backgroud Fatigue is considered as a common symptom in patients with end-stage renal disease (ESRD) and can significantly decrease patients' quality of life. This study aimed to assess fatigue in hemodialysis patients and to investigate risk factors of fatigue in Chinese patients receiving maintenance hemodialysis (MHD) in China. Methods Eligible patients completed questionnaires including demographic information, a Chinese version of the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue), the Family APGAR Index (APGAR), the medical outcomes study health status-Social Functioning subscale (SF-36,SocF), and the Pittsburgh sleep quality index (PSQI). Laboratory parameters were abstracted by medical records review. The multiple linear regression model was used to relate parameters with the FACIT-Fatigue score. Results A total of 345 MHD patients (216 men and 129 women, age 55.6 +/- 12.8) were recruited in this study. The score of FACIT-Fatigue was 39 (Interquartile Range, 31-44). Fatigue was correlated with PSQI scores (p<0.001), SocF scores (p<0.001), comorbidity (p=0.006), exercise time<1 hour per day (p=0.003), adequacy of dialysis (Kt/V)<1.2 (p=0.016), APGAR scores (p=0.014), and high Scr (p=0.043). Conclusions Fatigue is related to sleep disturbance, social and family functioning, taking physical exercise time, comorbidity condition, Kt/V and serum creatinine level in Chinese MHD patients. Future studies and interventions should focus on developing strategies and improving the quality of life in patients by addressing these significant contributing factors.
机译：Backgroud疲劳被认为是终末期肾脏疾病（ESRD）患者的常见症状，可能会大大降低患者的生活质量。这项研究旨在评估血液透析患者的疲劳并调查中国接受维持性血液透析（MHD）的中国患者的疲劳风险因素。方法符合条件的患者填写问卷，包括人口统计学信息，中文版的慢性病治疗疲劳功能评估（FACIT-疲劳），家庭APGAR指数（APGAR），医学结局研究健康状况-社会功能子量表（SF-36） ，SocF）和匹兹堡睡眠质量指数（PSQI）。通过病历审查提取实验室参数。多元线性回归模型用于将参数与FACIT-疲劳评分相关联。结果本研究共招募了345名MHD患者（216名男性和129名女性，年龄55.6 +/- 12.8）。 FACIT疲劳得分为39（四分位间距为31-44）。疲劳与PSQI评分（p <0.001），SocF评分（p <0.001），合并症（p = 0.006），每天运动时间<1小时（p = 0.003），透析充分性（Kt / V）<1.2相关（p = 0.016），APGAR得分（p = 0.014）和高Scr（p = 0.043）。结论中国MHD患者的疲劳与睡眠障碍，社交和家庭功能，体育锻炼时间，合并症，Kt / V和血清肌酐水平有关。未来的研究和干预措施应着重于解决这些重要的影响因素，从而制定策略并改善患者的生活质量。

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