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Prolyl isomerization: A new PIN code for DSB repair

机译:脯氨酰异构化:用于DSB修复的新PIN码

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摘要

Patients with acetabular dysplasia commonly undergo peri-acetabular osteotomy after skeletal maturity to reduce the risk of the late development of osteoarthritis. Several studies have suggested that deformity of the femoral head influences the long-term outcome. We radiologically examined 224 hips in 112 patients with acetabular dysplasia and early-stage osteoarthritis. There were 103 women and nine men with a mean age of 37.6 years (18 to 49). A total of 201 hips were placed in the acetabular dysplasia group and 23 in a normal group. The centre-edge angle and acetabular head index were significantly smaller (both p < 0.001), and the acetabular angle, acetabular roof angle and roundness index were significantly greater in the acetabular dysplasia group than those in the normal group (all p < 0.001). There were significant correlations between the roundness index and other parameters. Femoral head shape may be influenced by the severity of the acetabular dysplasia.
机译:髋臼发育不良的患者通常在骨骼成熟后进行髋臼周围截骨术,以减少骨关节炎晚期发展的风险。多项研究表明,股骨头畸形会影响长期预后。我们对112例髋臼异型增生和早期骨关节炎患者进行了放射学检查。有103名女性和9名男性,平均年龄为37.6岁(18至49岁)。髋臼发育不良组共放置201个髋关节,正常组共放置23个髋关节。髋臼发育不良组的髋臼角,髋臼头指数显着较小(均p <0.001),髋臼角,髋臼顶角和圆度指数均显着大于正常组(均p <0.001) 。圆度指数与其他参数之间存在显着相关性。髋臼发育不良的严重程度可能会影响股骨头的形状。

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