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Neuronal migration re-purposes mechanisms of cytokinesis

机译:神经元迁移改变了胞质分裂的机制

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摘要

The capacity of cells to transition through the cell cycle is among the most complex and carefully orchestrated in biology, and yet also among the most fundamental. A cascade of cytoskeletal events occurs that involves the coordination of microtubules and actin filaments, under the regulation of signaling pathways that include a variety of proteins. These pathways are so finely orchestrated that it would seem wasteful for them to be completely abandoned as differentiated cells permanently leave the cell cycle.
机译:细胞在细胞周期中过渡的能力是生物学中最复杂和精心策划的,也是最基本的。在包括多种蛋白质的信号传导途径的调节下,发生了一系列的细胞骨架事件,涉及微管和肌动蛋白丝的协调。这些途径经过精心设计,以至于由于分化的细胞永久离开细胞周期而被完全抛弃会显得很浪费。

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