• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Cell communication & adhesion >New Developments in the Gap Junction Field: Report from the 2002 ASCB Meeting
【24h】

New Developments in the Gap Junction Field: Report from the 2002 ASCB Meeting

机译：缝隙连接领域的新发展：2002年ASCB会议的报告

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Widespread interest in gap junctions was evident at the 2002 American Society for Cell Biology (ASCB) meeting in San Francisco as shown by the substantial attendance at over 30 presentations during a Gap Junction Special Interest Subgroup meeting, a Cell-Cell Junctions Mini-symposium, and two sessions of gap junction posters. The cell-to-cell channels present in vertebrate gap junctions allow diffusion of small molecules (<1000 MW) between adjacent cells and are composed of members of the connexin (Cx) family of gap junction proteins. This intercellular communication plays an important role in the control of cell proliferation, embryonic development, cell differentiation, and the coordination of differentiated cellular functions. Deficient or improper gap junction function has been associated with a variety of disease states, including some forms of neuropathy, hereditary deafness, cataracts, skin disease, heart disease, and cancer. Ablation of the genes in mice and zebra fish has revealed an even wider array of defects in both development and adult tissue function. These are summarized in Table 1.
机译：在2002年美国旧金山细胞生物学学会（ASCB）会议上，人们对间隙连接的广泛兴趣显而易见，这一点在Gap Junction特别兴趣小组会议，Cell-Cell Junctions小型专题研讨会，和两届间隙连接海报。存在于脊椎动物间隙连接中的细胞间通道允许小分子（<1000 MW）在相邻细胞之间扩散，并且由间隙连接蛋白的连接蛋白（Cx）家族成员组成。这种细胞间通讯在控制细胞增殖，胚胎发育，细胞分化以及分化细胞功能的协调中起着重要作用。间隙连接功能不足或不当已与多种疾病状态相关，包括某些形式的神经病，遗传性耳聋，白内障，皮肤病，心脏病和癌症。小鼠和斑马鱼中基因的消融揭示了发育和成年组织功能方面的缺陷更加广泛。这些总结在表1中。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号