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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Impact of prostate volume evaluation by different observers on CT-based post-implant dosimetry.
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Impact of prostate volume evaluation by different observers on CT-based post-implant dosimetry.

机译：不同观察者对前列腺体积评估对基于CT的植入后剂量学的影响。

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PURPOSE: An analysis of computed tomography (CT)-based dosimetry was performed to evaluate the variability of different observers' judgements in marking the prostate gland on CT films, and its effect on the parameters that characterise the prostate implantation quality. Accuracy of data entry by the first author in the process of dosimetry procedure has also been evaluated.MATERIALS AND METHODS: Four observers were asked to evaluate the prostate volume on CT films for six different patients. Each observer repeated the evaluation six times. The sample of patients has a prostate volume in the range of 21.4-42.0 cc derived from transrectal ultrasound volume study. After an average period of 6 weeks of the I-125 implantation, all patients had CT scans. CT-based post-implant dosimetry was performed and the dose volume histograms DVHs were calculated to report the re-constructed prostate volume, Vp100, Vp150, Vp90 and D90. Comparison between the four observers' output was performed.RESULTS: Comparison between the four observers shows that each observer has a different way of estimating the prostate on CT films. Observers' precision also varies according to the prostate volume and the image quality. This can cause a variation in the resulting D90 value by up to 50%. Analysis of data entry shows a high degree of accuracy. The error of digitizing the prostate is +/-0.19 cc. This is correlated to an error of +/-0.78 Gy of the D90.CONCLUSION: The evaluation of prostate gland volume on CT films varies between different observers. This has an effect on the dosimetric indices that characterise the implant quality in particular the D90.
机译：目的：进行了基于计算机断层扫描（CT）的剂量测定分析，以评估不同观察者在CT胶片上标记前列腺的判断的可变性，以及其对表征前列腺植入质量的参数的影响。还评估了第一作者在剂量测定过程中输入数据的准确性。材料与方法：要求四名观察员评估六位不同患者在CT胶片上的前列腺体积。每个观察者重复评估六次。患者样本的前列腺体积在21.4-42.0 cc范围内，取自经直肠超声体积研究。在I-125植入平均6周后，所有患者均进行了CT扫描。进行基于CT的植入后剂量测定，并计算剂量体积直方图DVH，以报告重建的前列腺体积Vp100，Vp150，Vp90和D90。结果：四个观察者之间的比较表明，每个观察者在CT胶片上估计前列腺的方式不同。观察者的精确度还根据前列腺体积和图像质量而变化。这可能会导致D90值的最大差异为50％。数据输入分析显示出很高的准确性。前列腺数字化的误差为+/- 0.19 cc。这与D90的+/- 0.78 Gy的误差有关。结论：CT胶片上前列腺体积的评估在不同的观察者之间有所不同。这会影响表征植入物质量的剂量指数，特别是D90。

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