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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Accuracy of seed reconstruction in prostate postplanning studied with a CT- and MRI-compatible phantom.
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Accuracy of seed reconstruction in prostate postplanning studied with a CT- and MRI-compatible phantom.

机译：使用CT和MRI兼容体模研究前列腺后计划中种子重建的准确性。

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BACKGROUND AND PURPOSE: Postimplant dosimetry of prostate seed implants is usually performed by seed localisation on transversal CT or MR images. In order to obtain reliable dosimetric evaluation data, it is important that seeds are reconstructed accurately. Currently, there is no comparative data available on seed localisation accuracy of CT-and MRI-based reconstructions, mainly due to the lack of a suitable QA tool. In this study, we developed a CT-and MRI compatible prostate phantom to investigate the intrinsic accuracy of seed detection for both imaging modalities. PATIENTS AND METHODS: A 60 seed geometry was created according to a clinically meaningful plan, including rotated and shifted seeds. After implantation of the seeds in the phantom, CT and MRI scans with 3, 4 and 5mm slice thickness were performed. The seed locations were reconstructed in the treatment planning system and compared with the known reference positions. RESULTS: Due to the comparable density and relaxation times of the phantom material to prostate tissue, the seeds are visualised similarly as on real patient images. The observed mean reconstruction uncertainties were in general smaller for CT (0.9+/-0.6, 0.9+/-0.6, 2.1+/-0.8mm on 3, 4 and 5mm scans, respectively), than for MRI (Philips 1.5T: 2.1+/-1.4, 1.6+/-1.2, 1.9+/-0.9mm on 3, 4 and 5mm scans, respectively, and Siemens 1.5T: 2.3+/-0.8, 2.0+/-1.6, 1.6+/-0.8mm on 3, 4 and 5mm scans, respectively). CONCLUSIONS: For our clinical sequences of both CT and MRI, the mean deviation of the reconstructed seed positions were all within acceptable limits for clinical use (<2.3mm). The phantom was found to be a suitable quality assurance tool to assess the reliability and accuracy of the seed reconstruction procedure. Moreover, as the phantom material has the same imaging characteristics as real prostate tissue, it is a useful device to define proper MRI sequences.
机译：背景与目的：前列腺种子植入物的植入后剂量测定通常通过在横向CT或MR图像上进行种子定位来进行。为了获得可靠的剂量评估数据，准确地重建种子非常重要。当前，由于缺乏合适的QA工具，目前尚无基于CT和MRI的重建种子定位精度的比较数据。在这项研究中，我们开发了CT和MRI兼容的前列腺体模，以研究两种成像方式的种子检测的内在准确性。患者和方法：根据临床上有意义的计划创建了60个种子几何形状，包括旋转和移位的种子。将种子植入体模中后，进行3、4和5mm切片厚度的CT和MRI扫描。在处理计划系统中重建种子位置，并与已知参考位置进行比较。结果：由于幻影材料与前列腺组织具有可比的密度和松弛时间，因此种子的可视化与真实患者图像上的可视化相似。一般而言，CT的平均重建不确定度要比MRI小（分别在3、4和5mm扫描时为0.9 +/- 0.6、0.9 +/- 0.6、2.1 +/- 0.8mm）（MRI，Philips 1.5T：2.1）在3mm，4mm和5mm扫描上分别为+/- 1.4mm，1.6 +/- 1.2mm，1.9 +/- 0.9mm，以及Siemens 1.5T：Siemens 1.5T：2.3 +/- 0.8、2.0 +/- 1.6、1.6 +/- 0.8mm分别进行3、4和5毫米扫描）。结论：对于我们的CT和MRI临床序列，重建种子位置的平均偏差均在临床使用的可接受范围内（<2.3mm）。发现该模型是评估种子重建程序的可靠性和准确性的合适质量保证工具。此外，由于体模材料具有与真实前列腺组织相同的成像特性，因此它是定义正确的MRI序列的有用设备。

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