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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >A comparison between 2-Step IMRT and conventional IMRT planning.
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A comparison between 2-Step IMRT and conventional IMRT planning.

机译：两步IMRT与常规IMRT规划之间的比较。

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BACKGROUND AND PURPOSE: 2-Step intensity modulated radiation therapy (2-Step IMRT) is an IMRT segmentation procedure based on analytical approximations [Bratengeier K. 2-Step IMAT and 2-Step IMRT: a geometrical approach. Med Phys 2005;32:777-785; Bratengeier K. 2-Step IMAT and 2-Step IMRT in three dimensions. Med Phys 2005;32:3849-3861]. The aim was to benchmark it with other IMRT algorithms and to establish it as planning tool for fast IMRT application with a reduced number of segments. MATERIALS AND METHODS: 2-Step IMRT plans were compared with IMRT-solutions obtained with methods from a commercial planning system (Pinnacletrade mark TPS). The four clinical cases chosen were: paraspinal tumour, carcinoma of the prostate, head and neck carcinoma and breast carcinoma. In addition the "Quasimodo" phantom study was used to compare the quality of the 2-Step IMRT method with respect to other planning procedures in the ESTRO study. RESULTS: The number of segments (and - to a minor degree - the monitor unitsper dose) of the majority of 2-Step IMRT plans was lower than for the commercial algorithms. The quality of the 2-Step IMRT-plan was comparable. In the Quasimodo comparison 2-Step IMRT plans with nine beams would place in the mid-range of all participants, whereas the 15-beam arrangements could compete with the best results. CONCLUSIONS: 2-Step IMRT is a valuable IMRT segmentation method, especially if the number of segments is to be limited (e.g. for reasons of precision, speed and leakage radiation).
机译：背景与目的：2步强度调制放射疗法（2步IMRT）是一种基于分析近似的IMRT分割程序[Bratengeier K. 2步IMAT和2步IMRT：一种几何方法。 Med Phys 2005; 32：777-785; Bratengeier K.二维二维IMAT和二维IMRT。 Med Phys 2005; 32：3849-3861]。目的是将其与其他IMRT算法进行基准比较，并将其建立为用于减少段数的快速IMRT应用的计划工具。材料与方法：比较了两步IMRT计划与通过商业计划系统（Pinnacletrade mark TPS）获得的IMRT解决方案。选择的四个临床病例是：脊柱旁肿瘤，前列腺癌，头颈癌和乳腺癌。此外，使用“ Quasimodo”幻象研究来比较两步IMRT方法与ESTRO研究中其他计划程序的质量。结果：大多数两步IMRT计划的段数（在较小程度上为每剂量监测单位）比商业算法要少。两步IMRT计划的质量是可比的。在Quasimodo比较中，九光束的两步IMRT计划将放置在所有参与者的中间范围，而15光束的安排可能会与最佳结果竞争。结论：两步IMRT是一种有价值的IMRT分割方法，尤其是在要限制分割数的情况下（例如，出于精度，速度和泄漏辐射的原因）。

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